Hi. I'm new to this forum. I've been on Zoloft (100mg) for 2 months. I have a debilitating side effect - it creates muscle spasms in my heat, jaw, neck & back. Not able to function normally. Pdoc put me on Trepiline 10mg a week ago, as it's a muscle relaxant. It has helped, although I am still having bad pain & earache. Has anyone has any experience with Zoloft causing painful muscle spasms? I would be most grateful for any input. Many thanks.