Hi there and thank you for visiting MedHelp's forums. We are happy to try to answer your question. First, your doctor is the best person to connect with for help on this subject. in answer to your question, yes. Taking antibiotics can affect your asthma. https://www.webmd.com/allergies/news/20040526/antibiotics-may-increase-allergies-asthma. However, there is some question also about whether it is the bacteria the antibiotics are treating that is actually triggering asthmatic symptoms. Speak to your doctor about this.