X linked agammaglobulinemia

[nick737]

Is it possible for one to have this disorder and not find out until they are twenty years old? I know I'm just being paranoid but I recently had an HIV test and I was concerned because I was wondering if it were possible for me to have this without knowing therefore making my negative results false. Sorry if this is a silly question I'm just having trouble finding info on the subject.

[nick737]

thanks Niko, the exposure I'm worrying about was almost a year and a half ago so I assume that even if I was immunodeficient, this would've allowed ample amount of time for antibodies to be created?

[TheLightSeeker]

If you are not being checked or treated for any autoimmune disease presently,
then you shouldn't be concerned.
Immunodeficiency, though,  not the same as autoimmune, may cause a delay perhaps in the production of the HIV antibodies, which is extremely rare.
An Immunologist would be able get you tested, to rule out this possibility.
Hope this helps.
Cheers!
Niko

[nick737]

One last question, is it possible for any autoimmune disorders to affect the outcome of an HIV test?

[nick737]

Hey Niko thanks for the information. Well I had a sexual encounter almost two years ago with someone I didn't know too well and truthfully, I had never even thought about testing until recently because I never had symptoms and I guess because of my lack of understanding of STDs in general, I assumed all of them had clear symptoms. I've never had any symptoms of anything but recently I've been paranoid so I decided to get tested. HIV was the thing I was most worried about especially because I wouldn't have even known if I had gotten it without a test. I was just playing all sorts of scenarios in my head thinking that maybe I had some immune deficiency that would prevent me from making antibodies after all this time creating a false negative. I know it's a ridiculous thing to think but the paranoia seemed to have gotten the better of me and I was just convinced that I had it despite my negative results.

[TheLightSeeker]

Hey nick737.

You are so right saying you are having trouble finding info
on this. It is a rare immune disorder where there's a lack of mature B cells
so there's no antibody  (immunoglobulin) production, therefore no immunne defense against infections.
If you want more info check my reply yesterday
to the post titled GAMMA M which is a distant variant of the X linked agammaglobulinemia presenting a γM globulin deficiency  and has quite a different profile as it is specific to this particular deficiency.
  X-Linked means that it affects only male children of
a non-symptomatic mother ( the carrier).


However,
It is not possible to have XLA without knowing, as the symptoms manifest from very young, often life threatening.
May I ask how you came up with this possibility? Just curious.
Was it because of the possible false-negative HIV test?

A false negative HIV test result is possible for various reasons,showing no antibodies even if a person has been infected, and I don't think XLA is one of them. The most common is because of the so-called " window period"
the start of the infection to the production of HIV antibodies-up to 6 months with typical being 6-12 weeks.
Hope this helps.
Niko
Take care,
Niko

[nick737]

can someone please answer me?