i hve been diganosed with severe depression . no suicidal thoughts ever , but feeling like running in a deep abbey of darkness, fear, and loss of desire to anything . this was usually accompanied by a desire for sleeping and escaping every activity. I have been descriped effoxor xr 150 for about one year and a half.. I felt better with less attacks, but depression never really disappeared . Now i feel the frequency of depression is increasing , I will c my doctor but am terrified of the idea of effexor losing efficacy . I wonder what is next ?