Hello and welcome to the forum. Thanks for the question and we are sorry to hear about your mother. Absolutely call her doctor about this situation and what she is experiencing. Memory loss and cognition issues are known to occur with this medication. Many years ago, a warning was issued about this side effect. However, there is also some conflicting data. For many, it is a safe choice in cholesterol lowering medication. https://www.mayoclinic.org/diseases-conditions/high-blood-cholesterol/in-depth/statin-side-effects/art-20046013 This is an interesting read on statins. Some people have memory loss and others have improvement in their dementia. This is very patient dependent. Lipitor can take two week to offer the reduced cholesterol and cardiac risk that goes along with that. At one week, yes, side effects could emerge. So, please talk to her doctor. Let us know what they say.