Anyone have worse anxiety & depression after starting Minocycline?

[Mit925]

Started 50mg Minocycline with dinner Saturday night for perioral Dermatitis. Woke on Sunday very depressed, unable to deal with people, very irritable & crying. Chalked it up to a bad depression day. Worse next day. No other changes. Nothing else to trigger worse depression & anxiety. 2 pharmacists & my psychiatrist all say this shouldn't be the case & I can't find any info on a google search. Has anyone else experienced depression or anxiety changes after starting Minocycline?  I have discontinued the med for now.

[Paxiled]

There are all kinds of side effects to taking antibiotics, and they should only be taken if absolutely necessary.  For one thing, there's the development of antibiotic resistant bacteria.  For another, they kill off beneficial bacteria as well as toxic ones, and some of these beneficial bacteria play a role in mental health,such as producing B vitamins.  The connection of probiotics to mental health is one of the hottest research topics in the medical field.  But anyone can have any reaction to a particular prescription drug; the body isn't adapted to any of them.  But be wary of quitting an antibiotic once you start taking it -- it can also produce antiobiotic resistance in your body.  Once you start you usually need to finish the dose.  In your case you quit pretty close to starting, but again, be careful doing this.  

[Paxiled]

And I should say I'm amazed you found no info on this from pharmacists or your psychiatrist, but I guess I shouldn't be -- only the best ones go further than what they learn about drugs from pharmaceutical company produced info.