sertraline vs. zoloft

[jtl712]

I used to be on zoloft for 4 yrs and felt good...stopped for 6 months and on my 3rd week of sertraline right now not feeling as good the first time around. Is there a difference with the two drugs?

[aperfectingangel]

My doctor told me that Sertraline and Zoloft both have the same ingredients but the pharmacutical companies can make them differently. I too notice a difference in how I feel taking Zoloft vs. Sertraline. I like Sertraline better though because I don't feel as numbed out and my sex drive is not affected.

[umya]

no difference.  just the name.  i have heard however, that sometimes the same antidepressant used for a second time after a break may be less effective.  this was told to me by a physician though another physician suggested otherwise.