Roughly 1 month ago, while I was masturbating, I noticed a kind of irritating spot under the gland of my penis. It was almost like there was a piece of dry skin on my hand and it was creating contact against my penis. I wouldn't describe it is a pain, more like a spot on my penis that felt a little odd with the friction of my hand on it. I noticed it a few times throughout the masturbation process. Anyway I woke up the next morning and I had a nice little red patchy area right where I felt that slight discomfort the night before. It was red, kind of sensitive feeling, I thought I had chaffed myself in all honestly. I gave it a week and to my surprise it was still there. I started to get concerned so I went to see my general practitioner and he thought it was a a fungal infection and proscribed lotrisone (cloritmazole and betamethasone). I used it for a week, maybe improved condition slightly, no major relief. I called him back, he prescribed me Diflucan, 3 pills, to take 3 days apart, at 200mgs a piece. By this point in time I was also noticing horrible itching and discomfort not only in my penis but also my scrotum and rectum. The diflucan seemed to really help my rectum but that spot on my penis it persisted. I began to use micronazole instead of the lotrisone, just to switch it up. I used it for roughly 1-2 weeks and took my Diflucan. Again my rectum got better, my penis stayed the same. I went and saw my MD again, he referred to a dermatologist but assured me it was nothing serious, no std, had to be a skin thing. So at this point I have tried antifungals, both oral and topical, I have been keeping great hygiene by showering daily and even washing my penis at the end of the night and eating yogurt thinking maybe it was a yeast infection. I also took supplements with acidophilus in it. For the love of god I dipped my penis in yogurt as a website advised to do for a male yeast infection. I slept naked for a few nights to get it air. I finally went to see the dermatologist and she looked at it, (this dermatologists was recommended as the best in the state) and she said "its nothing". I asked how it could be nothing and she said it is certainly not an STD and that she assumed it would go away. She gave me some emulsion cream to rub on it at night she said. Anyway enough said, I have had this going on for almost two months now. Prior to this whole thing breaking out, I really hadn't been doing anything out the the normal. The only things of note were these. Prior to the onset I was playing basketball at work and remaining in the same sweaty work clothes through the majority of the day (I have been gifted as a man with no BO, regardless of how bad I sweat), I have been stressed, I have not been sexually active in 6 months, and my girlfriend and I just split about 2 months ago. This brings me to a very important question. A question that has boggled my mind for months now. What the hell is on my penis? Should I cut it off? I am pretty frustrated and out of ideas.