Have you called and made your appt yet? I really am just trying to help when I first started hurting I was using my reg r and she kept telling me to find a PM dr but I kept putting it off she trie to refer me to some but I di not like them so I just kept sitting on my tail well she stopped giving me my meds said this is last rx call and get your app with PMdr. So I had to and soooo lad I did that was dr mangerei and he kept me pain free and he has a great bedside manner truly cares so I will stay on you till you get the appt. call your ast dr for referal if need be but GET APPT>
sandee
Odd medication responses is very common with CFS/FM. Usually it's hypersensitivity or opposite to expected reaction, rather than needing more. However, it may be the "opposite" contributing to needing excessive amounts.
The opposite is very funny, for instance, when Valerian root for sleep works so well as a stimulant in my mom and I that we compared our very productive nights awake. Cold meds to put you to sleep also perk me up but make me too groggy to be awake, yuk.
With pain killers, they can administer some of them without the epinephrine (spelling?), which can be an reactor for CFS. Maybe that's what's triggering your problem? Ususally it creates a kind of woozy stimulated effect.
Also, CFS bodies are slow to adjust, studies have literally show this. So, I haven't heard of slow to adjust to those particular drugs, but that might be your body's manifestation of it.
Part of what makes CFS/FM so challenging to treat is the extreme range of reactions to the same meds, with no way to predict.
You are not alone in this.