HIV test and blood anomalies question

[RodBrazilian]

My story:

I am 40 yo white male living a stable, trustful monogamous heterosexual relationship during the last 5.5 years. I never have any health problem of concern. In 2007, I was tested for STD, including HIV and all came back negative (HIV 1/2 Ab + P24 Ag).

In May 2013 (nearly six years later), I had a suspect of genital HPV, and the physician ordered a complete STD screen again (including HIV and HPV). Again, all came back negative. The HIV test were HIV 1 G24(ENV) and P24 (GAG) and HIV 2 GP36(ENV), with antigens specific for my blood type (“O”). Again, everything came negative, including HIV, HPV and Syphilis (which I was not screened in 2007).

In November 2013, my heart doctor asked me a complete blood count, along with other test (cholesterol, triglycerides, etc.). Everything was normal with the red cells, but the white cells were low (4090/mm3) and there were more leucocytes (2740/mm3) than neutrophils (920/mm3). She asked me about HIV and I replied her that I have been tested twice. One week later, I had an appointment with a nephrologist because a stone kidney problem, I showed the same complete blood count to him and he told me to do not worry about, because probably it was a result of a flu.

In December 2013 (exactly 45 days later), I had other complete blood count, the overall with cells count raised a bit (4540/mm3), but leucocytes (2588/mm3) and neutrophils (1362/mm3) were still unbalanced, although neutrophils raised nearly 1.5 times in relation to the former count.

This week I had a new complete blood count ordered by my gastrologist (I have reflux). Overall white cells was higher than 3 years ago (5470/mm3) as were leucocytes and neutrophils, but still more leucocytes (2976/mm3) than neutrophils (1882/mm3).

Of note, I must inform that I have never made sex without condom with one-night standers nor with short-term girlfriends and I also not do drugs (never did, by the way). Additionally, I must inform that I have sex regularly with my wife. Most of time with condoms, because she do not take birth controls of any type, but sometimes with no protection, including she swallowing my semen on a few occasions. She is a regular blood donor and she never had any STD detected in her donated blood (she have donated blood tree or four times since we start our relationship).

As a good hypochondriac, I read lots of information in internet and I am concerned with this persistent unbalanced leucocytes/neutrophils ratio.

Thus, I would like to now:

(1) Is there any chance of those two HIV tests be wrong? (sometimes I get paranoid imagining that they changed my blood with other patient!)

(2) Reference levels for blood counts vary widely, and sometimes what is a normal value for my white cell counts in one reference is not in others and this is driving me crazy! From the counts given above, am I having any problems with my white cells?

(3) What can be causing the unbalance between leucocytes and neutrophils? And which doctor should I seek to have a look on this?  Should I be worried?

Thank you in advance for your answers.  

[Claire_MHModerator]

Hi there,
When the ratio between the two counts is off, it just suggests inflammation somewhere in your body.  As a good hypochondriac, you probably already know that inflammation can be due to any illness.  The fact that you had 2 negative HIV tests 6 years apart -- after being monogamous with your wife -- indicates that you are conclusively negative for HIV.

[RodBrazilian]

Thank you, Claire!