NAT

[curemee]

hello,

would  a NAT test detect all subtypes of HIV, including O and N??

thank you

[mike_no]

NAT's are very different from the antibody test, the antibody tests looks for the immune response to the HIV. On the other hand, the NAT's detect the genetic material of HIV itself. NAT generally gives positive results much sooner than standard antibody testing would, making it useful in situations where early diagnosis is necessary. An RNA PCR test will produce a positive test result within two to three weeks. A DNA PCR test will provide positive results within three to four weeks (sometimes sooner)

Now, just like the antibody tests the NATs will not have the generic detection because they are very sensitive tests designed specifically for designated strands of the virus. Having said that, PCR HIV - 1 would detect;

1. Group M - A, B, C, D, F, G, H, J and K.
2. Group O
3. Group N

The HIV -2 and it's subtypes viz; A, B, C, D, E, F, G would be only detected by a PCR RNA / DNA HIV- 2

Coming back to your question - The recent RNA & DNA HIV - 1 PCRs do detect group O & N. However, you would have to also understand that Group O is very restricted to west-central Africa & Group N is extremely rare.

I hope that helps.

Mike

[curemee]

anyone else have any idea if a NAT will detect all subtypes???


thanx

[curemee]

btw, many states in america offer free NAT testing along with antibody tests....not just in blood donation screening

[curemee]

do you know if it would detect this rare strain??

thanx

[curemee]

well i've had an oraquick test and ive been told that oraquick tests for everything except subtype N.

i was wondering if a NAT would pick up subtype N??


thanx

[diver58]

NAT is not recommended for  primary screening and diagnosis. This is a tast done on donated blood samples. What is your concern?

[curemee]

anyone???