Aa
Aa
A
A
A
Close
Avatar universal

Can i change PEP

HI,

i got exposed to HIV through unprotected vaginal sex last Saturday. Sunday i went to hospital and unfortunately doctor was unavailable. Nurse advised me to take ZIDOLAM-N as PEP for 28 days. After continuing for 3 days i visited a doctor and he told me that Nevirapine should not be used for PEP but since i already started the PEP, he advised me to continue the same medication and asked to monitor closely the side effects of the drug. Now today Friday i am experiencing some pain in the upper abdomen.

Is there any possibility that i can change the PEP drug to avoid nevirapine, please Suggest?
5 Responses
Sort by: Helpful Oldest Newest
Avatar universal
People change drugs because drugs not agreeing with them.  But never stop PEP drugs without talking to your doctor.  Keep taking them.

He can give you other drugs and safely get you off the current ones if you are having any problems.

PEP is very effective.  A 2 year Mass. study showed 100% success.

But there is a case of a nurse who stopped for just 2 days -- the abstract didn't say why -- she tested negative at 4 weeks, which is a great sign, but tested positive at 6 weeks.  

Do whatever you can to help you stick it out.

Be well
Helpful - 0
Avatar universal
A DUO test after 28 days on PEP is not considered sufficient, but performed as part of the protocol.  So you should do it.  PEP can change the production of p24 antigens and may also change the production of antibodies.  Thus it can effect the normal interpretation of a conclusive result.

Some doctors will do a NAAT or PCR at 14 days in order to monitor.

You will have to wait 3 months and do an HIV test (preferable 4th gen test) for conclusive result (norm in US.)  

But you can do a DUO 1 month after stopping PEP also.  It should be highly indicative.  But follow your doctor's guidelines.

As far as PEP drugs, they can be changed; but you have to work with your doctor.  

Be well
Helpful - 0
Avatar universal
28 days after PEP with a DUO test
Helpful - 0
Avatar universal
i completed 28 days of PEP course and i tested for HIV DNA 2 days after PEP, result was negative and tested for p24 Antigen and Antibody(CMIA method) 9 days after completion of PEP, results were negative, negative.

How reliable above two test were?

My Doctor advised me to "Forget about the incident", does it mean i am completely safe?
Helpful - 0
480448 tn?1426948538
This is something you have to discuss with your doctor, we cannot advise you.
Helpful - 0
Have an Answer?

You are reading content posted in the HIV Prevention Community

Top HIV Answerers
366749 tn?1544695265
Karachi, Pakistan
370181 tn?1595629445
Arlington, WA
Learn About Top Answerers
Didn't find the answer you were looking for?
Ask a question
Popular Resources
Condoms are the most effective way to prevent HIV and STDs.
PrEP is used by people with high risk to prevent HIV infection.
Can I get HIV from surfaces, like toilet seats?
Can you get HIV from casual contact, like hugging?
Frequency of HIV testing depends on your risk.
Post-exposure prophylaxis (PEP) may help prevent HIV infection.