Aa
need ans pls
Is there any difference if DUO test at done at 27 days and 28 days?
pls
pls
No difference in one day.P24 antigen will peak between 3 to 4 weeks.That test is 99.89% reliable at this time frame.
In this quote below, our own Dr. HHH explains very well why you will see varying advice when it comes to the window periods and testing times:
The confusion about seroconversion time (window period) comes from three main sources.
First, failure to understand that not all HIV tests are the same. Older antibody tests took longer than current ones, but not all web sites or public health agencies have caught up with the difference. Also, testing often now includes direct tests for the virus, such as PCR for HIV DNA and tests for p24 antigen. For the combination of such a test plus antibody testing (e.g., the "4th generation", "duo", or "combi" test), the window period is only 4 weeks. By that time, all infected people will have a positive result on one or both components of the two tests.
Second, legal conservatism. Some agencies lean over backward to take no chance of telling someone they don't have HIV if they may be infected. Their legal departments advise going even further than scientifically necessary in their advice about window periods. That's where you may see advice about 6 months, even though all antibody test manufacturers claim their tests are 100% reliable by 3 months.
Third, regulatory issues. A company producing a new HIV test may validate it by studying blood from a few thousand persons, of whom some are known to have HIV and others are known not be infected. For those with HIV, the company's research team may decide to only study persons with infection known to be present 3 months or more. The test may in fact detect everyone infected for 6 weeks or even less. But since they have only studied those infected for 3 months or more, the US Food and Drug Administration (FDA) requires them to say a negative result may not be reliable until 3 months have passed.
For the antibody tests, the last issue is the most confusing. Everything known about the speed with which antibody develops in response to a new HIV infection, and the ability of the tests to detect that antibody, indicate that the tests will pick up virtually all new infections by 6 weeks, and certainly by 8 weeks. But because of the regulatory standards, the manufacturer may not claim 100% reliability until 3 months. And given the manufacturers' stance, it's easy to understand why physicians, clinics, health departments, or other agencies feel they need to stick with 3 months in their formal advice.
I hope this helps clarify these issues. For more information, see these threads as well (read them all -- the main information is in the follow-up comments).
http://www.medhelp.org/posts/show/1347755
http://www.medhelp.org/posts/show/1177982
Best regards-- HHH, MD
The confusion about seroconversion time (window period) comes from three main sources.
First, failure to understand that not all HIV tests are the same. Older antibody tests took longer than current ones, but not all web sites or public health agencies have caught up with the difference. Also, testing often now includes direct tests for the virus, such as PCR for HIV DNA and tests for p24 antigen. For the combination of such a test plus antibody testing (e.g., the "4th generation", "duo", or "combi" test), the window period is only 4 weeks. By that time, all infected people will have a positive result on one or both components of the two tests.
Second, legal conservatism. Some agencies lean over backward to take no chance of telling someone they don't have HIV if they may be infected. Their legal departments advise going even further than scientifically necessary in their advice about window periods. That's where you may see advice about 6 months, even though all antibody test manufacturers claim their tests are 100% reliable by 3 months.
Third, regulatory issues. A company producing a new HIV test may validate it by studying blood from a few thousand persons, of whom some are known to have HIV and others are known not be infected. For those with HIV, the company's research team may decide to only study persons with infection known to be present 3 months or more. The test may in fact detect everyone infected for 6 weeks or even less. But since they have only studied those infected for 3 months or more, the US Food and Drug Administration (FDA) requires them to say a negative result may not be reliable until 3 months have passed.
For the antibody tests, the last issue is the most confusing. Everything known about the speed with which antibody develops in response to a new HIV infection, and the ability of the tests to detect that antibody, indicate that the tests will pick up virtually all new infections by 6 weeks, and certainly by 8 weeks. But because of the regulatory standards, the manufacturer may not claim 100% reliability until 3 months. And given the manufacturers' stance, it's easy to understand why physicians, clinics, health departments, or other agencies feel they need to stick with 3 months in their formal advice.
I hope this helps clarify these issues. For more information, see these threads as well (read them all -- the main information is in the follow-up comments).
http://www.medhelp.org/posts/show/1347755
http://www.medhelp.org/posts/show/1177982
Best regards-- HHH, MD
No, one day will not make a difference with any kind of testing.
As for the differences in testing advice, we go over this all of the time. WE advise people to test as per the official CDC guidelines and the guidelines set by the testing manufacturers, which in both cases, is 3 months. The doctors will say a conclusive result can be obtained much earlier. You can decide to do what you want in regards to testing, but our recommendations remain the same, that a 3 month negative is conclusive.
As for the differences in testing advice, we go over this all of the time. WE advise people to test as per the official CDC guidelines and the guidelines set by the testing manufacturers, which in both cases, is 3 months. The doctors will say a conclusive result can be obtained much earlier. You can decide to do what you want in regards to testing, but our recommendations remain the same, that a 3 month negative is conclusive.
I did not receive any answers regarding DUO test.
If Dr HHH is saying duo test is conclusive @ 28 days in the expert forum I wanted to know about only DUO. Is it same as 27 days?
if 3 months is only conclusive then is Dr HHH is giving wrong info.
I have seen him saying to one guy who had *** with known positive after 4 weeks negative to not to re tset and
conclusive
If Dr HHH is saying duo test is conclusive @ 28 days in the expert forum I wanted to know about only DUO. Is it same as 27 days?
if 3 months is only conclusive then is Dr HHH is giving wrong info.
I have seen him saying to one guy who had *** with known positive after 4 weeks negative to not to re tset and
conclusive
You've already received many answers, here is just ONE of your threads:
http://www.medhelp.org/posts/HIV-Prevention/Need-Some-experts-advice/show/1742703#post_7991649
No need to keep asking the same question over and over. Our answers are not going to change.
http://www.medhelp.org/posts/HIV-Prevention/Need-Some-experts-advice/show/1742703#post_7991649
No need to keep asking the same question over and over. Our answers are not going to change.
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