There are biological treatments that can either dissolve the vegetations (clots) or at a minimum, stabilize it until the body can eliminate the clot. Anticoagulant medication (heparin, warfarin, etc.) can prevent any further clotting (stabilize) or a more potent agent (streptokinase, urokinase, tPA, etc,) which actively dissolve clots. Can be delievered with minimum intervention directly to the site of interest or no intervention with injection to the blood stream.