Iodine Anemia Questions for the researchers

[Mikkimoe]

Hi all - I'm still hanging in there on week 2 of SOC plus Enbrel but am moving like a snail with enphazema. They lost my week 1 PCR - go figure, week 2 is tomorrow. (I'll camp out till i get my results). Either Hemaglobin is dropping fast or this Iodine thing or probably both (My Hmg was kind of low to start: 13.1)

Have a question about my lab 3 weeks ago - did some research and found this article - does this mean I may be Iodine deficient?

Per this article  - it may indicate that I have Iron anemia or latent deficiency (may be part of why I'm so whipped out). But I'm pretty brain dead so could be reading this wrong.

My MCV on my last lab was 83.4, My RDW-CV was high at 15.6.
On a 2/26 lab my iron saturation was low at 14
Per this article I would fall into the highlighted area below. (whoops won't highlight it's the 79+or - 7fl, 15.6+or-.7%)


Change in red blood cell distribution width with iron deficiency.

Uchida T.

First Department of Internal Medicine, Fukushima Medical College, Japan.

Red cell volume distribution width (RDW-CV) was examined as a means of diagnosing iron deficiency. Iron deficiency was classified as iron deficiency anaemia, prelatent or latent iron deficiency in 1648 students. MCV and RDW-CV (mean +/- ISD) in each group were 89 +/- 4 ft, 12.7 +/- 0.7% in normal individuals, 89 +/- 4 fl, 13.2 +/- 0.8% in prelatent deficiency, 86 +/- 6 fl, 14.0 +/- 1.5% in latent deficiency, and 79 +/- 7 fl, 15.6 +/- 1.7% in iron deficiency anaemia, respectively. Although microcytosis was evident only in iron deficiency anaemia, RDW-CV showed larger values concomitant with the development of iron deficiency. The sensitivity of RDW-CV for the diagnosis of iron deficiency anaemia was 77.1%, and for iron deficiency anaemia and latent deficiency 49.2%, the specificity being 90.6%. In countries with a high prevalence of iron deficiency and low thalassaemia, iron deficiency should be screened by RDW-CV determination without serum iron or ferritin measurements.

Thanks - Mikki

[Mikkimoe]

Duh - Your right that's Iron deficiency..Ok I'm like a snail with emphysema and alzheimers.

Actually feeling a bit better today. Blood test was good. Your right Mouse the white is dropping. From 8.2 to 6.1 in 2 weeks. The Hemo is good at 13.1. Is the Procrit for the white cells or the Hemo? Whats the Neupogen for?

Here's the awesome thing my ALT went from 124 to 37 - in just 2 weeks -pretty amazing  eh? No wonder i feel like **** - this is working!
Don't have my VL for a few more days.
What day of the week do you take your Humeria in respect to the Peg?
I'm seperating them by 3 days - the doc doesn't know so says it's up to me.

Thanks

[charm27]

They lost your PCR? Just want you wanted to hear.Nothing surprises me but Im sorry to hear that. You feel like a snail with emphysema already at week 2?? Im sorry to hear that too! I didnt feel that way till week 7.

I hope you feel better and make sure you have sure labs checks every couple of weeks.
Best of luck on tx.

Charm

[FloridaMouse]

I think you are asking if you have an "iron" deficiency type anemia.  It is possible but you really should get your doc to interpret for you.

I take Humira (a biologic like Enbrel) for my RA and I'm 19 weeks into treatment now.  I'm seeing my doc tomorrow to start on either Procrit or Aranesp for anemia.  I don't think the biologics affect the red cell/hemaglobin as much as they will affect the white cell count.

Do you know where you hemaglobin is at now?

Mouse