Creatinine is 1.1 on Tenofovir & eGFR is 86%

[smile_boy]

I'm on Tenofovir for past 7 Years and My Serum creatinine is 1.1 mg/dL and eGFR is 86 % . Rest all the parameters like BUN,URIC acid are normal. LFT is normal and HBV PCR is undetected for past 7 years

Should I bother about the eGFR value ?

[stef2011]

check cystatin c it will tell you if you have damage

[melcul]

Do you have any idea if a white meat diet and normal salt intake significantly affects creatinine / egfr ?

[smile_boy]

Thanks Stef. My cystatin c is  1.4 mg/L where normal range is <= 1.03mg/L. What your opinion on this ? Should I change to TAF now?

[smile_boy]

Should I be worried now?

[stef2011]

definitely change to TAF, is bone density ok?

[smile_boy]

Sure Stef.  Have to check the bone density. Please let me know what tests I should do ?

[stef2011]

dexa scan

i also had an increase of creatinine from 0.8-0.9 to 1.27 (max 1.3) and cystatin C 0.97 (max 0.95), bone scan -1.5.i should recover al of them by 1 year on entecavir

[melcul]

You have to watch the trend, how were your results over the years ? Did egfr consistently went down, or is it alternating ?
For example i had once 95 egfr, and the next result was 115. It depends on your water intake as well. It should be a minimum of 2L / day.
But definitely keep an eye on it

[smile_boy]

I think it is consistently went down. My Creatinine value was constantly around 1.0 to 1.1 after starting tenofovir .