Aa
Is Entecavir 0.5 safe after becoming lamivudine resistant?
After taking lamivudine for about 1.5 years my mother's sgpt/sgot levels suddenly rose to 206 and 131 respectively (from 38 and 41 respectively 3 months back) along with a hbv dna of 18,00,000 iu/ml.But she has been asymptomatic throughout.We consulted another hepatologist who said that she had become lam-resistant thereby recommended her to take Entecavir 0.5 daily and get the tests done after 3 months.Her recent test results are:sgpt=40,sgot=44,hbv dna =1,64,000 iu/ml.The doctor is satisfied with this result and has asked her to continue with the treatment and repeat the tests after another 3 months.Now my question is that is she totally safe under ETV treatment or in the future there can be another issue with resistance.....?
Best Answer
absolutely, it is not possible to prescribe lam today even for very poor country tenofovir generics from india are very very cheap
Thank you for your quick response.Should I change the doctor and look forward to take tdf?
if yo are naive to etv there is almost no resistance, 1.2%, it is only being resistant already to lam or telbivudine that makes etv useless.
this said tenofovir is the only drug with 0% resistance with naive or lam resistance patients
this said tenofovir is the only drug with 0% resistance with naive or lam resistance patients
I'm on baraclude 0.5mg since 2010. Everything seems fine. I'm still positive for HBsAg , negative for HBeAg and Positive HbBeAb.
The treatment seems to go well. I'm constantly worried about become resistant. I don't believe in using the same drug for a long time without the virus learning to mutate to prevent drug from killing them. Eventually, all viruses and bacteria will learn the system and evolve.
The treatment seems to go well. I'm constantly worried about become resistant. I don't believe in using the same drug for a long time without the virus learning to mutate to prevent drug from killing them. Eventually, all viruses and bacteria will learn the system and evolve.
Entecavir treatment after Lam resistance is not that much safe. Tenefovir is absolutely better option if she does not have a problem in her kidneys.
Have an Answer?
You are reading content posted in the Hepatitis B Community
A list of national and international resources and hotlines to help connect you to needed health and medical services.
Herpes sores blister, then burst, scab and heal.
Herpes spreads by oral, vaginal and anal sex.
STIs are the most common cause of genital sores.
Condoms are the most effective way to prevent HIV and STDs.
PrEP is used by people with high risk to prevent HIV infection.
