bad news on binarapant ?

[80percenthidebrain]

I just read this news now.. it is sad to hear it.. any one know about this issue ?

http://seekingalpha.com/news/2493936-tetralogic-stops-enrollment-in-birinapant-hep-b-trial-shares-plummet

[Scaredpreg]

Oh my. Looks like the hope for Binirpant has quickly turned around. I wonder if there's a condition this person had which triggered this side effect.

[Royal36]

We can't wait for full recovery in two weeks & proceed with their trials. Finger crossed!!!!

[studyforhope]

it is hard to predict how the fda will react. the recovery process from the palsy and speed will also determine that. it should only take 2 weeks to recover, but i dont know if they will use methylcobalamine to speed up recovery.

[twinboys1girl4me]

Good to know.  This initially worried me as I do know someone that got Bell's out of the blue and is still completely debilitated for over 2 years now, without much improvement and tons of therapy.  

Do you think they will restart the trial if others want to go forward, or do you think the FDA will shut it down?  You are very knowledgeable and I am very new to the background of how trials function.  I was really hoping for great news from this one, as I know we all were.  Let's just hope it's not a complete wash.  

[sorte]

thanks man !! the part hope in your nickname is well deserved, study as well btw :)

[studyforhope]

The Bell's palsy caused by BIRINAPANT is not the same as regular spontaneous Bell's palsy. It will typically disappear fast upon discontinuation of the drug. Methyl cobalamin injections will speed up recovery and might possibly have preventative effects. However i doubt that the situation is handled this way.
We do not know at which dose level and what frequency this problem occurred. One can only hope that the trial will continue after it has cleared up.