Aa
How are your teeth post triple tx??
Knock, knock, Penny?? Knock, knock, Penny??
Hi there everyone. Haven't been on the boards in awhile, as I have been dealing with multiple health issues since tx (which failed for me). My doc doesn't think it's due to tx, since the drugs are out of my system. I am a little past 1 year post tx w/Victrelis, Peg & Riba. Because we ALL have had some ailment in our lives before tx, and because I definitely have pre-existing stuff, I don't want to jump to blame everything on the tx meds.
That said......I just found out that I need Major dental work. Multiple cavities, holes, and missing pieces of a tooth. Granted, I have not been keeping up with regular dental visits but I certainly do not believe I have done anything that would cause something so drastic. So, for the Post Treatment folks, please share if you have experienced unusual dental changes that lead you to believe it could be Interferon related, or the other tx meds. And if you have links to any fact based articles, please include those too. Quite embarrassing to think this is my doing, so if I could provide my dentist with another valid reason.... Too sleepy to research tonight.
Thanks in advance.
Sending a big HI!!! to all my old MedHelp buddies (2011-2012).
Be Blessed,
Bee :0)
Hi there everyone. Haven't been on the boards in awhile, as I have been dealing with multiple health issues since tx (which failed for me). My doc doesn't think it's due to tx, since the drugs are out of my system. I am a little past 1 year post tx w/Victrelis, Peg & Riba. Because we ALL have had some ailment in our lives before tx, and because I definitely have pre-existing stuff, I don't want to jump to blame everything on the tx meds.
That said......I just found out that I need Major dental work. Multiple cavities, holes, and missing pieces of a tooth. Granted, I have not been keeping up with regular dental visits but I certainly do not believe I have done anything that would cause something so drastic. So, for the Post Treatment folks, please share if you have experienced unusual dental changes that lead you to believe it could be Interferon related, or the other tx meds. And if you have links to any fact based articles, please include those too. Quite embarrassing to think this is my doing, so if I could provide my dentist with another valid reason.... Too sleepy to research tonight.
Thanks in advance.
Sending a big HI!!! to all my old MedHelp buddies (2011-2012).
Be Blessed,
Bee :0)
Best Answer
In defense of Frank..... I think he was trying to convey that in spite of his best attempts to take care of himself......
1) he sought to cure his Hep C
2) he sought to care for his teeth via an oral care professional and used those treatments which are recommended HERE as a prophylactic measure....... and to no avail.
.....he did the best that he could using professional care.....
The end result was that he looked as though he has been indifferent about his outcome or worse, that HE had been the problem with them.
He sounds traumatized by his end result, extremely self conscious. See if your compassion can cut both ways....
He was trying to help, not hurt.
His choice of adjectives may not have been politically correct or accurate, but he was trying to convey an idea.
I am reminded of a line from a recent Geoge Clooney film (Up in the Air) where somebody chastises him for stereotyping.
http://www.youtube.com/watch?v=_uNPpFZLelE
Of course.... if you want the thread to change topics...by all means....
willy
1) he sought to cure his Hep C
2) he sought to care for his teeth via an oral care professional and used those treatments which are recommended HERE as a prophylactic measure....... and to no avail.
.....he did the best that he could using professional care.....
The end result was that he looked as though he has been indifferent about his outcome or worse, that HE had been the problem with them.
He sounds traumatized by his end result, extremely self conscious. See if your compassion can cut both ways....
He was trying to help, not hurt.
His choice of adjectives may not have been politically correct or accurate, but he was trying to convey an idea.
I am reminded of a line from a recent Geoge Clooney film (Up in the Air) where somebody chastises him for stereotyping.
http://www.youtube.com/watch?v=_uNPpFZLelE
Of course.... if you want the thread to change topics...by all means....
willy
Asle -- Well Said! I agree.
Frank -- I hear what you're saying in terms of tx related dental complications (you should get that checked out) but duuuudddde....this is Not a forum for stereotyping remarks. Venting -- yes.
Pooh -- Thanks VERY much for these links!! Things escalated after I posted and I am having oral surgery tomorrow. So this will be great info to have in hand, especially since they may not have factored in what I went through with the TX meds.
Thank you again everyone for sharing! I wish you well on your journeys, during and after tx.
Blessings,
Bee
Frank -- I hear what you're saying in terms of tx related dental complications (you should get that checked out) but duuuudddde....this is Not a forum for stereotyping remarks. Venting -- yes.
Pooh -- Thanks VERY much for these links!! Things escalated after I posted and I am having oral surgery tomorrow. So this will be great info to have in hand, especially since they may not have factored in what I went through with the TX meds.
Thank you again everyone for sharing! I wish you well on your journeys, during and after tx.
Blessings,
Bee
I am sorry to disappoint you with my description asle.
I do apologize to you and anyone else if I offended anyone else.
It was very insensitive of me and I hope my apology will be accepted.
I was not thinking and being a bit depressed about it all. Sorry again.
frank
I do apologize to you and anyone else if I offended anyone else.
It was very insensitive of me and I hope my apology will be accepted.
I was not thinking and being a bit depressed about it all. Sorry again.
frank
I'm just a little disappointed about your description of '.........probably looks like I am some drug addict! It is really disgusting!.' etc
What does a drug addict look like? Like an alcoholic? A scumbag? A homeless person? A disgusting representative of the human race?
As we are all trying here to repair our bodies from contracting HCV, it is NOT important how we contracted it. We have all been non-judgemental here.
I'm sorry about your mouth problems post TX. I too am having a rough 'mouth' time during Tx, and am trying not to to pre-empt the consequences.
What does a drug addict look like? Like an alcoholic? A scumbag? A homeless person? A disgusting representative of the human race?
As we are all trying here to repair our bodies from contracting HCV, it is NOT important how we contracted it. We have all been non-judgemental here.
I'm sorry about your mouth problems post TX. I too am having a rough 'mouth' time during Tx, and am trying not to to pre-empt the consequences.
Thanks for this post and those links/articles!
I have always had sensitive teeth but always tried to take care of them.
I was with a great dentist during treatment and he really was taking sensitive care of my teeth but when my teeth started snapping off suddenly I was so embarrassed and so depressed I stopped going.
I had even been prescribed a special mouth rinse for dry mouth but it didnt help!
Now after "the cure" and all these years of being disabled from it all my teeth are still feeling the effects! I fear that if I go see someone they will want to pull them all out. I am probably exaggerating (maybe not)... but it seems very bad to me as a year goes by and one or two break off! It probably looks like I am some drug addict! It is really disgusting! and I am "cured" and have been off the meds for many years! What a mess!
I have always had sensitive teeth but always tried to take care of them.
I was with a great dentist during treatment and he really was taking sensitive care of my teeth but when my teeth started snapping off suddenly I was so embarrassed and so depressed I stopped going.
I had even been prescribed a special mouth rinse for dry mouth but it didnt help!
Now after "the cure" and all these years of being disabled from it all my teeth are still feeling the effects! I fear that if I go see someone they will want to pull them all out. I am probably exaggerating (maybe not)... but it seems very bad to me as a year goes by and one or two break off! It probably looks like I am some drug addict! It is really disgusting! and I am "cured" and have been off the meds for many years! What a mess!
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5.7 Dental and Periodontal Disorders
Dental and periodontal disorders have been reported in patients receiving ribavirin and interferon combination therapy. In addition, dry mouth could have a damaging effect on teeth and mucous membranes of the mouth during long-term treatment with the combination of ribavirin and interferon alfa-2b.
http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=9ed7adc9-bd0c-41af-b34c-43d15a7799d1
Teeth and gum disorders, which may lead to loss of teeth, have been reported when this medicine is used in combination with interferon alfa or peginterferon alfa.
http://www.netdoctor.co.uk/infections/medicines/copegus.html
This medicine may cause teeth and gum problems. This medicine may cause dryness of the mouth, and a dry mouth may damage your teeth and gums if you take the medicine for a long time.
http://www.mayoclinic.com/health/drug-information/DR602577/DSECTION=precautions-
Dental and periodontal disorders
: Dental and periodontal disorders, which may lead to loss of teeth,
have been reported in patients receiving ribavirin and peginterferon alfa-2b or interferon alfa-2b
combination therapy. In addition, dry mouth coul
d have a damaging effect on teeth and mucous
membranes of the mouth during long-term treatment with the combination of ribavirin and
peginterferon alfa-2b or interferon alfa-2b.
http://www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Product_Information/human/001018/WC500056547.pdf
Severe Stomatitis Complicating Treatment With Pegylated-Interferon
-2a and Ribavirin in an HCV-Infected Patient
http://health.usf.edu/NR/rdonlyres/F05CA297-F2AA-4F28-8B76-5A65378B24A6/44993/IFNStomatitis.pdf
In a Japanese Phase III trial of Peg-IFN alfa-2a and ribavirin involving 199 patients with chronic hepatitis C, including 99 patients with IFN treatment-naive genotype 1 and 100 patients with patients whom had not had a SVR after IFN therapy, the oral side effects were: gingival bleeding and gingival swelling (6%), toothache (4.5%), gingivitis and periodontitis (3%), dental caries (1.5%), stomatitis and cheilitis (19.1%), disorder of taste (15.6%), dry mouth (6.5%), glossalgia and glossitis (4.5%), perioral paresthesia (2.5%), oral pain (0.5%), oral mucosal damage (0.5%), oral lichen planus (0.5%), oral hemorrhage (0.5%), dry lip (0.5%), and bulla of lip (0.5%). On the other hand, in a Japanese Phase III trial of Peg-IFN alfa-2b and ribavirin involving 332 chronic hepatitis C patients, including 269 patients for 48 weeks treatment duration with genotype 1b and high virus load, and 63 patients for 24 weeks treatment duration with others, oral side effect were: dental pulpitis, gingivitis, and periodontitis (8.9%), toothache (7.1%), dental abnormity (1.1%), stomatitis and cheilitis (26.8%), disorder of taste (26.8%), dry mouth (15.6%), glossitis (5.9%), oral discomfort feeling (2.6%), oral hemorrhage (0.4%), oral pain (0.4%), dry tongue (0.4%), decreased secretion of saliva (0.4%).
http://www.virologyj.com/content/7/1/192
Hope this helps some.