Aa
I did a liver biospy, two 2/4, 2/4 , whats that mean?
my doctor told me it's moderate demage, I am Hepatitis B carrier, E-positive, 10E8, very high level, ALT/AST 57/55, my doctor told me don't treat until next test, but I am really worring about it, someone told me most case will end with liver cancer. I am near 40 and have two kids to feed..
Tons thanks, I post on the hepb they suggested me to come here because they said experts are here. thanks a lot, I will discuss it with my doctor.
I didn't read your post thoroughly and realized you have hepb instead of hepc. The treatment protocol is very different for hepb but the stage and grade information provided is the same. You may want to post on the hepb forum to get more detailed information.
Trinity
Trinity
“Stage” is the amount of fibrosis (scaring) detectable by biopsy…
from stage one (mild) to four (cirrhosis ). Fibrosis is scar tissue that forms as a result of chronic inflammation and/or extensive liver cell death . Your health care provider uses the amount of fibrosis in your liver as one way of evaluating how quickly your disease appears to be progressing. knowing when you were initially infected with HCV is a great help in determining your rate of disease progression.
The Stage is assigned a number from 0-4:
• 0 = no scarring
• 1 = minimal scarring
• 2 = scarring has occurred and extends outside
the areas in the liver that contains blood vessels
• 3=bridging fibrosis is spreading and
connecting to other areas that contain fibrosis
• 4=cirrhosis or advanced scarring of the liver
“Grade” is the amount of inflammation , which is caused by the activity of the virus. Generally speaking, inflammation is the precursor to fibrosis .
The Grade is assigned a number based on the degree of inflammation , which is usually scored from 0-4 with 0 being no activity and 3 or 4 considered severe activity. The amount
of inflammation is important because it is considered a precursor to fibrosis.
You have moderate damage to your liver. Some people with stage 2 decide to wait for better treatments that should be available within the next couple of years. Your liver health will not improve without successful treatment but this disease can take a long time to severely damage the liver. Genotype determines the length of treatment - geno 1's treat 48 wks, geno 2"s & 3's treat 24 wks. Discuss your options with your doctor and decide what is best for you. If you drink alcohol, I would stop immediately because alcohol will accelerate damage. If it were me, I would treat but that is a personal decision.
Good Luck and welcome to the forum.
Trinity
from stage one (mild) to four (cirrhosis ). Fibrosis is scar tissue that forms as a result of chronic inflammation and/or extensive liver cell death . Your health care provider uses the amount of fibrosis in your liver as one way of evaluating how quickly your disease appears to be progressing. knowing when you were initially infected with HCV is a great help in determining your rate of disease progression.
The Stage is assigned a number from 0-4:
• 0 = no scarring
• 1 = minimal scarring
• 2 = scarring has occurred and extends outside
the areas in the liver that contains blood vessels
• 3=bridging fibrosis is spreading and
connecting to other areas that contain fibrosis
• 4=cirrhosis or advanced scarring of the liver
“Grade” is the amount of inflammation , which is caused by the activity of the virus. Generally speaking, inflammation is the precursor to fibrosis .
The Grade is assigned a number based on the degree of inflammation , which is usually scored from 0-4 with 0 being no activity and 3 or 4 considered severe activity. The amount
of inflammation is important because it is considered a precursor to fibrosis.
You have moderate damage to your liver. Some people with stage 2 decide to wait for better treatments that should be available within the next couple of years. Your liver health will not improve without successful treatment but this disease can take a long time to severely damage the liver. Genotype determines the length of treatment - geno 1's treat 48 wks, geno 2"s & 3's treat 24 wks. Discuss your options with your doctor and decide what is best for you. If you drink alcohol, I would stop immediately because alcohol will accelerate damage. If it were me, I would treat but that is a personal decision.
Good Luck and welcome to the forum.
Trinity
there are two 2/4, 2/4, it's stage 2 level of fibrosis, and stage 2 level of infection, I am wondering what stage 2 mean? how serious it's ? is it recoverable?
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