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Coffee and SVR?

Hello All,
I heard that people who drink 2-3 cups of coffee a day, have better chances of attaining SVR. Was wondering if anyone on this site heard a similar thing.
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Avatar universal
Thanks pooh, I'm really grateful. I take around three cups a day so that might be a reason of my attaining RVR from baseline VL of 4,500,000 (rounded) .
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1815939 tn?1377991799
Yes, I have read similar information. I will list a few links that discuss this subject.

"Coffee Consumption and Response to Peginterferon and Ribavirin Treatment in Patients with HCV Infection

"In order to determine whether consuming larger amounts of coffee can improve response to treatment in patients with HCV infection, Freedman and associates examined coffee intake and response to treatment using data from the lead-in phase of the HALT-C trial. Enrolled patients (n=885) had HCV infection and fibrosis or cirrhosis at baseline, exhibited no signs of hepatic decompensation or hepatocellular carcinoma, and had failed to respond to interferon therapy. Patients recorded coffee intake before re-treatment with peginterferon α-2a (180 μg/wk) and ribavirin (1,000–1,200 mg/day). The investigators assessed patients for early virologic response (2 log10 rseduction in HCV RNA level at Week 12; n=466) and undetectable levels of HCV RNA at Week 20 (n=320), Week 48 (end of treatment; n=284), and Week 72 (SVR; n=157). Patients who consumed more than 3 cups of coffee per day had twice as great a decline in HCV RNA viral load from baseline compared to nondrinkers (median 4.0 vs 2.0 log, respectively). After adjusting for sex, age, race/ethnicity, alcohol use, presence of cirrhosis, ratio of aspartate aminotransferase to alanine aminotransferase, interleukin-28B genotype, interferon dose reduction, and other factors affecting response, patients who drank the most coffee remained approximately twice as likely to respond to treatment. Response rates were significantly higher in heavy coffee consumers compared to nondrinkers at all time points (early virologic response: 76% vs 46%, respectively; Week 20 response: 52% vs 26%, respectively; SVR: 26% vs 11%, respectively). These findings, which were published in the June issue of Gastroenterology, suggest that heavy coffee consumption is an independent predictor of improved virologic response to peginterferon and ribavirin treatment in patients with HCV infection."




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Avatar universal
Please share if anyone heard a similar thing.
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