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Avatar universal

Do Dr.'s usually prescribe phenergan or compazine for TX related nausea?

I have been pondering (possibly worrying a bit) about my husband trying TX #4 with Victrelis.  If we could manage nausea better this  time, it would help so much. After months of suffering, they finally gave him some compazine last time and it did help.
I have been looking at the drug phenergan and wondering if it would help more.  There may be a reason that compazine is being chosen over phenergan for this particular use but I haven't been able to get to the bottom of that question yet.  ( I recall Mike Simon saying that compazine was a life saver for him.) Do some Dr.'s prescribe phenergan instead.  One website I read said that compazine is better for opiod related nausea and phenergan is better for gastroenteritis and inflammation related nausea and vertigo.  That description sounded more like what TX causes, maybe. The pherergan is also an antihistamine. A pharmacist told me they are very similar yet a website I was reading said they are very different.  
If anyone has an opinion, I'd like to hear it.
Thank you,
Ev
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1726450 tn?1316282511
I second the sea-bands, they are also listed for use in nausea related to chemo.
They are an accu-pressure bracelet.

I also chew on raw ginger-helps tons.You can brew it in tea also.

My Dr. did prescribe me Phenegran , but I have only taken it twice so far. It makes me drowsy.

I am on Incivek instead of Victrelis.
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Avatar universal
Just a thought but has anyone ever tryed Seabands for the nausea? I get very car sick, sea sick and they are wonderful. I did read on the package that they can be used for other nausea related issues. Pregnant women use them, verdigo, same principle as the scopalimine except they work like accupunture. They sell them in the pharmacy next to dramine. Again just a thought. And no extra meds going into your body.
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264121 tn?1313029456
he!!.  I took zofran, phenergan (I get dystonic on compazine), and if I had thought about it, I would have asked for some scopalimine patches too.
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Avatar universal
Lapis,
Generic Zofran was still very expensive.  I can't remember how much but I remember gasping. :>)
Thank you,
Ev
-----------------
aj7538-I hope you will be lucky and not have much nausea.  My husband has cirrhosis which probably makes him more prone to this SX on TX.  It is interesting that your Dr. considered Comp. milder.  In the poking around that I have done so far, I haven't heard that one is harder than the other on the liver but both go through the liver. (don't know about Zofran)  
Joe got URQ pain if he took Comp.  as frequently as they said he could.  He was worried he'd cause a problem for his poor old liver so he only took it when he absolutely had to.  That is one of the main reasons that lead to me to ask about phenergan instead.  If you don't have cirrhosis, you won't have to be as concerned.
Best wishes on your TX,
Ev
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Avatar universal
The compazine puts you to sleep too.  At least I see there wasn't a reason not to try the phenergan.
Thanks,
Ev
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Avatar universal
Thank you,
Your answer came through while I was writing an addendum.  It is too bad that Zofran is so expensive.  Joe is on disability because of the cirrhosis and medicare didn't think the excessive cost of Zofran was worth it.  They are probably right considering the frightful cost of the TX meds , not to mention the terrifying price tag per vial  of Procrit.  If we didn't still have a grade school child at home, I don't think Joe would be doing this again.  
Thanks,
Ev
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Avatar universal
i have not started tx yet but discussed with my dr about what to take if I get nausea and he suggested compazine my understanding was it was milder than some of the.other drugs aj7538
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683664 tn?1330966324
I was given Zofran during my tx with Incivek.  The insurance company fussed and the nurse practitioner had to go back and forth with them a bit.  Seems it's approved for cancer chemo but they haven't yet figured out that HCV tx is also chemo.  I think that's the big benefit of Zofran, it doesn't cause the drowsiness.  I wonder if the cost is any better by now.  Anyway, it really worked for me even at the lowest dose.
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Avatar universal
Forgot to add, they worked great for the  nausea, but they sure made me drowsy.
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Avatar universal
phenergan 25 MG is what my hepo ordered me when i was on boceprevir, i'm also cirrhotic. Hope he has good luck this time.

cando
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Avatar universal
By the way, I know about Zofran also but it was prescribed to Joe last time when the compazine wasn't working that well, but our insurance said no because it is much more expensive.  There is a generic Zofran now but it also is way more expensive than Phenergan and Compazine. I should have added that Joe didn't do all that much actual vomiting but he had lots of dry heaves.  We tried some of the ginger cures also but no miracles there.  I didn't give him ginger capsules because they are blood thinning and Joe's platelets are so low that I don't want to mess with that.
Ev
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Avatar universal
I used Zofran and compazine in the past (not on tx) Zofran If it's okay for him to take had no sides and worked the best for me, i've heard others say the same thing.
Good luck,
Dave
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