Very interesting article. I hope those heppers whose Drs cut them off at 8 weeks because not UND will show this article to those same Drs.
Praying that, by now, they ARE UND and on the way to SVR, but having evidence to back up a claim for continued tx for what I consider that critical extra 4 weeks is excellent!
On to SVR, All!
Pat
Nice! More proof that there is more collective data here than most doctors know!
Dee thanks for always looking out for this "Community". Great article!
......Kim
You guys are so great! Thank you! I saw this, thought about people being detected at 8 weeks hoped this would help them
Dee
Along the lines of information. I just saw the first commercial from the CDC re HCV. It is the Know More HCV Campaign. It said that people born between 1945 and 1965 are FIVE TIME'S more likely to have HCV. They are now saying there are more than 4M in US with HCV. 3 out of 4 infected were born during those 20 years. I hope people get the word. 75% of people infected don't know.
Thanks so much, I thought it was interesting, Dee
Great article, Dee. Lucinda is amazing. Thanks for posting it.
" I hope those heppers whose Drs cut them off at 8 weeks because not UND will show this article to those same Drs"
Are you referring to patients who were prescribed and started 12 or more weeks of the new drugs then having their tx stopped at week 8 if VL detected? Except for a 10 fold increase in VL.
Where there any members who posted that this happened to them? If so what did they do?
I know there are member here with GT1 VL under 6M who started 8 week tx. and are trying to get 4 more weeks. This article wouldn't support that in my opinion.
I am on the 8 week tx did a viral load at 3 weeks was 108 doing another viral load Tuesday that will be week 4 for me my doctor told me I will be fine and will need the additional 4 weeks my pre tx viral load was 2million so it dropped from that to 108 Does this make sense?
Corredition doctor said won't need the additional 4 weeks.
Darn phone.... Can't type today, sorry folks.
It's 2 week VL. 2000000 to 108. I believe you will be undetected or maybe det un 12 at 4 weeks and will achieve SVR. In my opinion some posts by some members although well intentioned may cause unnecessary worrying for others and that "may be unhealthy"
I was in a similar boat last year when I started tx GT2. Cirrhosis SOV/RBV 12 weeks and had read 16 weeks might be better. I mentioned it once or twice and expressed a little concern but concentrated on tx. and didn't worry about it
I am optimistic I shall achieve svr and so is my doctor.I will see what the viral load is by the end of next week. Thanks.
I was directing it mainly at the 2 or 3 who posted that because they were not undetected they were terminating tx. I believe those posts were in Dec or Jan but could be wrong.
Also, my intent toward those who were given an 8 week tx protocol, to try for 12 weeks, if they felt uncomfortable w/8 weeks tx. I haven't seen anything from the AASLD saying that 8 weeks was the accepted protocol, even on Harvoni, even thought we have people who are clearing in 8 weeks.
Am I wrong? Has AASLD changed their recommendations for SOC for Harvoni?
If so, please correct me, and point me to the info. I do not want to give out incorrect info.
Thanks
pat
It is acceptable with * ..." identified lower relapse rates in patients receiving 8 weeks of ledipasvir/sofosbuvir who had baseline HCV RNA levels below 6 million IU/mL (2%; 2 of 123), and was the same for patients with similar baseline HCV RNA levels who received 12 weeks (2%; 2 of 131). This analysis was not controlled and thus substantially limits the generalizability of this approach to clinical practice. Shortening treatment to less than 12 weeks should be done with caution and performed at the discretion of the practitioner"
AASLD/IDSA/IAS–USA. HCV testing and linkage to care. Recommendations for testing, managing, and treating hepatitis C.
http://www.hcvguidelines.org/full-report/initial-treatment-hcv-infection
Accessed April 11, 2015
Note it is possible that some health professionals and or insurance may have access to more current data than what is officially reviewed and or published.
I read that report and forwarded it to my doctor on Friday it appears the 1a's as I am should consider the 12 weeks and the 1a's and 1a's fair better. They mention caution should be taken when prescribing 8 weeks, so I shall see after next week viral load to see if we will push for the 12 weeks. I am tx naive gt 1a F2 viral load 2million. Who knows?
Typo 1a's fair better.... Darn
1b....for the third time.
Genotype 1b treatment-naive patients
There is no measurable difference demonstrated to date in treatment response to ledipasvir/sofosbuvir for HCV genotype 1 subtypes, thus the supporting evidence remains the same as for HCV genotype 1a–infected patients (see Genotype 1)
AASLD/IDSA/IAS–USA. HCV testing and linkage to care. Recommendations for testing, managing, and treating hepatitis C.
http://www.hcvguidelines.org/full-report/initial-treatment-hcv-infection
Accessed April 11, 2015
Best wishes
Thanks! I appreciate the update----now, if I can just remember that there IS a time so I can look it up! : -)
Pat
I must have misread then I thought there was a difference good to know I have to reread the article.
I see the date is April the article from I was reading was in January 2015