And just keep on Keeping on!
SVR for all - however the meds get us there!
(From Lucinda Porters RN post above)
Don't despair if you have detectable virus during or at the end of HCV treatment.
Be sure your doctor doesn't stop treatment just because you have detectable HCV RNA. The HCV guidelines recommend viral load testing after 4 weeks of therapy and at 12 weeks following treatment completion. If quantitative HCV viral load is detectable at week 4 of treatment, repeat viral load testing at treatment week 6. If viral load has increased by greater than 10-fold on repeat testing at week 6 (or thereafter), then discontinuation of HCV treatment is recommended. There are no other recommendations to stop or extend therapy based on viral load results.
Hi I was trying to give hope to people who did not get to UND early. Sorry if this scared anyone. That definitely was not my intention.
Dee: Thanks for the comment. I totally agree! : -) Pat
Sorry so late to respond, this article reminded me of Fred who's doctor stopped tx at 8 weeks. I think it is so important to find a doctor who has real time experience with tx. It is so frustrating to treat in the first place, then to be cut off is heartbreaking.
Thanks
bumping up for others to see
It is the same document I read it states caution should be taken when prescribing 8 weeks. That was my concern. I am sure I will be ok seeing I am below 6 million the relapse was 2% if I remember correctly.
I got a similar typing problem on my LG G2 April 11, 21015 ?? couldn't even imagine that far in the future.
It isn't an article, it's a living document that can be updated at anytime. The important thing is to revisit before acting on any recommendations.
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AASLD/IDSA/IAS–USA. Recommendations for testing, managing, and treating hepatitis C. http://www.hcvguidelines.org. Accessed April 11, 2015
http://www.hcvguidelines.org/news/how-cite-and-permissions Accessed April 11, 2015
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I try not to quote hcvguidelines.org material without revisiting site as I did today to be sure it hasn't been updated since my last visit. When I use April 11, 21015 that tells everyone that I checked today to verify the info I quoted
I see the date is April the article from I was reading was in January 2015
I must have misread then I thought there was a difference good to know I have to reread the article.
Thanks! I appreciate the update----now, if I can just remember that there IS a time so I can look it up! : -)
Pat
Genotype 1b treatment-naive patients
There is no measurable difference demonstrated to date in treatment response to ledipasvir/sofosbuvir for HCV genotype 1 subtypes, thus the supporting evidence remains the same as for HCV genotype 1a–infected patients (see Genotype 1)
AASLD/IDSA/IAS–USA. HCV testing and linkage to care. Recommendations for testing, managing, and treating hepatitis C.
http://www.hcvguidelines.org/full-report/initial-treatment-hcv-infection
Accessed April 11, 2015
Best wishes
1b....for the third time.
Typo 1a's fair better.... Darn
I read that report and forwarded it to my doctor on Friday it appears the 1a's as I am should consider the 12 weeks and the 1a's and 1a's fair better. They mention caution should be taken when prescribing 8 weeks, so I shall see after next week viral load to see if we will push for the 12 weeks. I am tx naive gt 1a F2 viral load 2million. Who knows?
It is acceptable with * ..." identified lower relapse rates in patients receiving 8 weeks of ledipasvir/sofosbuvir who had baseline HCV RNA levels below 6 million IU/mL (2%; 2 of 123), and was the same for patients with similar baseline HCV RNA levels who received 12 weeks (2%; 2 of 131). This analysis was not controlled and thus substantially limits the generalizability of this approach to clinical practice. Shortening treatment to less than 12 weeks should be done with caution and performed at the discretion of the practitioner"
AASLD/IDSA/IAS–USA. HCV testing and linkage to care. Recommendations for testing, managing, and treating hepatitis C.
http://www.hcvguidelines.org/full-report/initial-treatment-hcv-infection
Accessed April 11, 2015
Note it is possible that some health professionals and or insurance may have access to more current data than what is officially reviewed and or published.
I was directing it mainly at the 2 or 3 who posted that because they were not undetected they were terminating tx. I believe those posts were in Dec or Jan but could be wrong.
Also, my intent toward those who were given an 8 week tx protocol, to try for 12 weeks, if they felt uncomfortable w/8 weeks tx. I haven't seen anything from the AASLD saying that 8 weeks was the accepted protocol, even on Harvoni, even thought we have people who are clearing in 8 weeks.
Am I wrong? Has AASLD changed their recommendations for SOC for Harvoni?
If so, please correct me, and point me to the info. I do not want to give out incorrect info.
Thanks
pat
I am optimistic I shall achieve svr and so is my doctor.I will see what the viral load is by the end of next week. Thanks.
It's 2 week VL. 2000000 to 108. I believe you will be undetected or maybe det un 12 at 4 weeks and will achieve SVR. In my opinion some posts by some members although well intentioned may cause unnecessary worrying for others and that "may be unhealthy"
I was in a similar boat last year when I started tx GT2. Cirrhosis SOV/RBV 12 weeks and had read 16 weeks might be better. I mentioned it once or twice and expressed a little concern but concentrated on tx. and didn't worry about it
Darn phone.... Can't type today, sorry folks.
Corredition doctor said won't need the additional 4 weeks.