Isnt this trial taking geno 4`s
http://www.clinicaltrials.gov/ct2/show/NCT00869661?term=RO5024048&rank=2
Thanks Rocker for pointing out this trial.Was not aware of it.
Looks like my study location (NYC) is not recruiting yet.
What do you know about RO5024048 (R7128) ?
I have no clue as to what to expect from this. I only know that I am currently naive
and I am looking for the best possible shot which excludes placebo
and SOC by itself.
As a geno 4 should I do Alinia plus SOC or the trial you mentioned above?
What would you do ?
Scroll down to post :"Back From The Doctor",a a member Tom is investigating the same trial,you may wanna check it out.I dont know whole lot but good luck.
thanks , I read thru it.
This new drug seems to be promising yet in a trial setting I might get placebo
and end up straight SOC which for geno 4 means about 50-60% SVR and 48wks
pretty much for sure.They have 5 arms one being placebo. So that is a 20% chance
of getting placebo. According to Egypt trials from Romark I have a 21% chance
of not getting my SVR with Alinia+SOC.
With Alina it is a possible 79% @48wks and 36wks with early response.
Than there is the 17% chance of clearing Alinia mono. Small but true.
Also if I turn out to be a non responder or relapser on Alinia+SOC I will
have the PIs to retreat with in the future.
A Chief hepatologist told me this as for retreating with Telepravir after Alinia +SOC :
sustained virologic response rate is in the 40% range for nonresponders and 60-70% range for relapsers
Of course that is when Telepravir becomes available they will let me retreat with it
being geno 4.
If I were to do this trial and somehow fail there are no good fall back scenarios
right now.
The whole thing is like a big chess game only that it is not a game!
Anybody with Tx experience is welcome to weigh in please!