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Avatar universal

I relapsed on SOVALDI and Ribavirin

I have Hep-C G2.
Started SOVALDI and Ribavirin 12 week treatment Dec 23, 2013 (viral load at 2.5 million),
within 4 weeks into treatment my Hep C virus was undetectable.
12 weeks end of treatment my Hep C virus was undetectable.
4 weeks after treatment my Hep C virus was undetected.
12 weeks after of treatment my Hep C virus was detected at 83,000 viral load. It relapsed.

What are my chances of a cure now?
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766573 tn?1365166466


What dose of Riba were you taking.
The Sovaldi insert has this

Dose of ribavirin is weight-based (<75 kg = 1000 mg and ≥75 kg = 1200 mg). The daily dose of ribavirin is
administered orally in two divided doses with food. Patients with renal impairment (CrCl ≤ 50 mL/min) require
ribavirin dose reduction; refer to ribavirin prescribing information.

https://www.gilead.com/~/media/Files/pdfs/medicines/liver-disease/sovaldi/sovaldi_pi.pdf
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Avatar universal
What was yor duration on each of your treatments and I did you reach undection durning treatment?
Helpful - 0
Avatar universal
Guess I'll be treating again in December. Got the news last week that I too relapsed g2b. This was my second time treating. Don't know what combo I'll be doing this time. Previous sovaldi/ribb.   Peg and ribb. Here we go again peace
Helpful - 0
9662954 tn?1405606159
I heard that two go's worth sovaldi seems to have the highest rate of SVRs....so, as I might be doing, do it again! October is when the new single pill, 12 week treatment begins.

Good luck! Dbz
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Avatar universal
I'm certainly no expert, but when you talked about your size it resonated with me a bit because my hepatologist told me that me being 135 and 5'6 gave me good odds (or she hoped) because I was (weight and size proportionate) and these drugs are so new, perhaps they are hammering out dosing as it relates to weight, size, etc....In terms of length of treatment, dosing, etc. To me that's just a guess - I'm not saying anything definitive because I'm no doctor or medical researcher, but I think you're expressing a salient point when you talk about what your doc told you. I just wish you the best and I'm hoping the next time will be the charm for you. I haven't been here much lately (haven't been feeling well due to prolly a number of things, one of which is withdrawing from these drugs, though most people seem to have a much easier time of it) Really, best to you.
Helpful - 0
Avatar universal
I just received my Liver Biopsy results: ZERO fibrosis.
My doctor said that I most likely relapsed because 12 weeks of sovaldi and ribavirin was not long enough due to my size (6',5" 250lb)
I am scheduled to start treatment again, sovaldi and ribavirin 24 weeks
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