IV ozone therapy Hepatitis C 100% effective in irradicating for good?

[robby123]

Hepatitis C - IV ozone therapy over 6 treatments 100% effective in irradicating for good?

[il_editore]

http://www.ncbi.nlm.nih.gov/pubmed/21417811

There are some positive results with ozone therapy, no one is claiming a cure.

[IAmTheWalrus]

All of the recent information that I have read indicates that initial viral load is not a very good predictor of SVR. Much more important are genotype, genetics, metabolic syndrome, insulin resistance (related to ms) and initial response to treatment.

On the other hand, something that reduces viral load can't be all bad :-)

[Willy50]

I am unaware of the relationship with starting viral load.  Common thought was that it would take more time to eliminate a higher viral load than a low, but that would be also assuming the same immune response, of which we have greatly differing responses.  

And so my unscientific observation is that some people with high viral loads sometimes rapidly respond, some with low viral loads may not.

I think it is also useful to clarify that we are talking about starting viral load where you start at some sort of equalibrium w/ your immune response. (or contrasted with a 4 week SOC lead in as with Victrellis before adding the PI)

My point, which was speculative was that various other methods of viral reduction might be used in conjunction with, for instance w/SOC.

If it were true that you could "clear" using one of these methods (safely also being a caveat) then SOC for a reduced time might be possible, or triple therapy for 12 weeks; you get the idea.

I believe the IV milk thistle served as a polymerase inhibitor; it just made me think that if used with current triple therapy it would in effect become quad therapy.  
The idea generally, if that the more pathways that get blocked in reproduction the more effective the blocking.  It may be that some of these other blood treatments may be more like pathogens such as by oxidation, which might mean something that would not produce resistant mutations, thereby perhaps working synergistically with the other forms of TX.
(and the same reason that adding IV milk thistle infusions to a TX w/ a polymerase inhibitor might just be redundant and add little or nothing)

willy

[desrt]

My thinking is that starting with a low viral load probably only has a positive predictive value for SVR if it it is something your body has achieved on its own. (Like the 'European protocol' that allows geno 1s to treat for 24 weeks with just Peg/riba if they meet certain conditions.)
This is similar to the mindset that was popular 6 years ago on this site, where people thought that by subjecting themselves to toxicly high doses of Peg/riba and becoming 'artificial undies', they could then go back and apply the statistics based on normal dosages to predict their responses.
You can't have it both ways.

[willbb]

there a correlation between starting VL and SVR? Maybe that's a known for most, but it isn't for me. I'm assuming there is a better chance of SVR with a lower VL given your remark about starting at 0?
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With the advent of the new DAA's the amont of baseline VL is not near as important to SVR as it was with just the old SOC  (Peg Riba) ,   however I believe you are doing just Peg/ Riba within a trial so there would be some significance.

Good luck ..
Will

[FaithforHealing]

Willy,
Very interesting and insightful information. I wish I had been aware of these homeopathic tx's that appear to be effective in lowering viral load, I would have looked into them during all the years I was waiting for my time to start SOC. Which made me wonder, is there a correlation between starting VL and SVR? Maybe that's a known for most, but it isn't for me. I'm assuming there is a better chance of SVR with a lower VL given your remark about starting at 0?
My other question is whether or not taking oral milk thistle has ever been shown to be effective to any degree, or is it just the IV?
Thanks,
FFH