SciClone Pharma's Zadaxin for Non-responder

[SenorD]

http://www.hepatitis-central.com/mt/archives/2008/06/phase_3_hepatit.html

the article said:  Phase 3 trial evaluating ZADAXIN® (thymalfasin) as a potential third component for Hepatitis C traditional combination therapy has just been completed.  
Was anyone on this trial or heard about this drug?

[DoubleDose]

I do know how to spell 'would'...apparently my keyboard does not!  I hate typos...especially my own!

DD

[DoubleDose]

The above posts are absolutely correct!  Zadaxin has proven to add NO benefit to SOC therapy for HCV, and if used alone wouold probably be about as effective as a placebo, or some vitamins and herbs.  I am really amazed at how long this ineffective drug has dragged along, looking for some application where they might find a glimmer of added benefit, and hence an opportunity to finally sell the stuff.  I think it will continue to die a slow, long, fitful death, while the developers of the drug continue to look for some sort of market opportunity.

My doctor told me over six years ago that all prior tirals with Zadaxin had shown negligible benefit, and that it wouold be a waste of time and money to try to add it to tx.  He turned out to be right on the mark. I have not seen a convincing study yet using the big "Z".

  Look to the new "inhibitor" class drugs currently in development and testing,.... Protease, Helicase, Polymerase Inhibitors, all moving toward trials, and many looking toward final approvals by FDA in coming years.  Cocktails of these drugs, combined with SOC will probably work in even the toughest cases.  Get a top notch HCV doctor, and explore upcoming trials, etc. with them.  You need a solid game plan.

DoubleDose

[JennyPenny]

Miles and I both did zadaxin at the same time and it didn't work for us. The only nice thing about zadaxin was its lack of side effects.

[desrt]

I can't get your link to work, but I thought that Zadaxin had been shown not to be a valuable addition to SOC. It would be nice if it were, but I thought research on this had ended a couple years ago.
MKAndrew, I think, tried it on one of his tx attempts, without any luck.