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autoimmune disorders

I have a auto-immune disorder called Sjogrens which makes me ineligable for the the treatment for Hep-C. Will this new protease treatment be effective for me?
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Avatar universal
penn:  TMC435

http://www.hepctrust.org.uk/News_Resources/news/2011/July/TMC435+for+HCV+Gets+Fast+Tracked+Studied+with+PSI7977
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Avatar universal
The non-INF treatment is expected, by the drug company itself, to be on the market in 2013.  It's just been fast-tracked by the FDA


Which one? BMS or Gilead or PSI?
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Avatar universal
Yes, INF can trigger auto-immune disorders and once you have one, you are more susceptible to others.  INF treatment has it's risks in regard to auto-immune conditions.

The non-INF treatment is expected, by the drug company itself, to be on the market in 2013.  It's just been fast-tracked by the FDA.  I don't know what stage of liver damage you have but I hope this will be hopeful news for you.  In the meantime, there are others who are not able to do treatment who are using various strategies to contain progression of their liver disease.  Perhaps you're doing that already.  Some of those folks post here and they would be happy to share with you if that's something of use to you.

Trish
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148588 tn?1465778809
The treatment that includes a protease inhibitor still also includes interferon. If your doctor doesn't want you to treat, it's probably because of the interferon which can worsen auto-immune disorders. Treatments that don't include IFN are still in the experimental stage and will probably be a few more years coming, if they happen.
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Avatar universal
It has been documented that
Sjogrens often manifests itself because  of having HCV... so you were told you can not do therapy  because of it?

Will
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