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Statistics for reaccuring Cirrohis in post transplant patients
Hi, had liver transplant in 06. Fibrosis is now redeveloped. I am on interferon and rib. Have been for about year. Viral load has been lessoned. Wondering, what the stats are for my type of situation in regards to developing cirrohis again-should the treatment not arrest the virus. I am a 56 year old male.
Hi
Even though you havent become UND at this stage, after being on treatment for a year, the interferon is be maintaining your liver and possibly reversing some damage done.
Maybe this is why the doctor is willing to keep you on treatment or it may be that liver transplant patients need a different course of action. I know of one lady who had a transplant that did the interferon for a year, she became undetected but after the 6 month post treatment, the virus had returned, so they put her back on the treatment for another year, higher dose. Pity they didnt test her 2 months after treatment, instead of wasting all that time.
HCA is right, liver transplant recipients progress to cirrhosis faster.
There was a study done where they kept the patients on interferon for a couple of years, at low doses and it didnt show much response. To me it was obvious that they would need higher doses, but it was a study. I dont know if liver transplant patients were included.
Might be a good idea if you can get a second opinion.
Even though you havent become UND at this stage, after being on treatment for a year, the interferon is be maintaining your liver and possibly reversing some damage done.
Maybe this is why the doctor is willing to keep you on treatment or it may be that liver transplant patients need a different course of action. I know of one lady who had a transplant that did the interferon for a year, she became undetected but after the 6 month post treatment, the virus had returned, so they put her back on the treatment for another year, higher dose. Pity they didnt test her 2 months after treatment, instead of wasting all that time.
HCA is right, liver transplant recipients progress to cirrhosis faster.
There was a study done where they kept the patients on interferon for a couple of years, at low doses and it didnt show much response. To me it was obvious that they would need higher doses, but it was a study. I dont know if liver transplant patients were included.
Might be a good idea if you can get a second opinion.
If it hasn't been eliminated after a year it won't be eliminated at all-this is not my opinion it is accepted and proven medical science.The virus is interferon resistant and it is not good for you to take the medication without a reasonable chance of cure.
There are other interferon based treatments and new drugs which work with interferon.
I ask again what genotype do you have?
Where are you (what country) ?
There are options for you,but from what you have said you need to try a different interferon at least.
There are other interferon based treatments and new drugs which work with interferon.
I ask again what genotype do you have?
Where are you (what country) ?
There are options for you,but from what you have said you need to try a different interferon at least.
HI, they are keeping me on treatment as they feel there is still a chance for its elimination. This was agreed on by myself, as i feel there is more to gain then loose. Granted the side effects are challenging at times. What other treatment are you referring to?
It has been known for some years that Hep C progression is more rapid in donated livers than in the original liver.Age is probably a major factor in this phenomenon.
As fibrosis has developed you should expect it to progress-'fibrosers fibrose' as my doctor is fond of saying.
It seems you have been on interferon for 'about a year' and still have detectable viral serum.It is very odd that they have kept you on for this long when you have not cleared.
You need a new treatment plan and probably a new doctor.
What genotype do you have?
As fibrosis has developed you should expect it to progress-'fibrosers fibrose' as my doctor is fond of saying.
It seems you have been on interferon for 'about a year' and still have detectable viral serum.It is very odd that they have kept you on for this long when you have not cleared.
You need a new treatment plan and probably a new doctor.
What genotype do you have?
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