off label sovaldi (sofosbuvir) with olysio (simeprevir)

[wrayc]

Hello

I'm HBV -1a with VL about 5 mil
Fibrosure 4/3
Biopsy 2/2

I have no income or insurance
Recently prescribed sovaldi with pegintron and ribavarin

Im in poor general health and quite nervous about the sides of this regimen

How likely is it that I can persuade my GI to swith me to sofosbuvir with simeprevir
thereby avoiding interferon and ribavarin
as opposed to the current approved SOC?? (sovaldi+riba+interferon)

I believe I'm getting my meds through donations based on income etc
so ins co. to deal with


thanks for the input

[can-do-man]

Since you did have the biopsy I would rely on that more then the fibrosure test, way more accurate and if I remember correct your blood counts like platelets were good. Since you are treatment naïve one would think it would be hard to convince a doctor to treat any different then what yours is doing. The thing is you need to rid yourself of this now and looking at what a 12 week course?

Treatment will be over before you have to deal with much of the side effects, you got a chance to do this at no cost so go for it... Best to you.

[wrayc]

thanks for the input can-do-man
my platelets tend toward low end normal
around 150k... slow slide from 200 in past 7 yrs
bilirubin 0.7
ast/alt 80/120
i'm actually HCV, not hbv the other was typo
I have burning hands and feet in the past year or so
which I believe is indicative of cirrhosis
I haven't gotten the meds yet
but my doc submitted the necessary forms last week
costs aside, I can't see why any doc would choose to subject their patients to the known risks and sides of riba and ifn with the new options available
but cost is major issue
I agree, the game plan is to treat and cure

thanks again