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potential false positive hep c antibody test-please help
I just received a positive hep c antibody test. The cut-off was <1.00 and my result was 1.04. I am extremely worried and have taken a quantitative pcr w/rfx test, I'm awaiting the results. My liver enzymes were also elevated (which makes my doc think it is not a false positive) My AST enzymes were at 147 with the range at 10-30. I have read that lifting weights can cause this to rise, and I did lift weights 3 days prior to this test when I hadn't before. Any input on my results? I am going crazy over this. I am a young mom with two boys and ZERO risk factors other than one incident that I will explain below. My doctor told me not to kiss my kids and to use a different toilet which is making me so much worse. The only potential risk factor (which is why I got tested in the first place) was because a vascular surgeon I was going to was injecting the varicose veins on my legs with a needle (called sclerotherapy), accidentally pricked his own finger through his glove, and continued using that needle on me. I am going out of my mind. Any input is sooooo appreciated. Thank you!
Best Answer
http://www.mayomedicallaboratories.com/test-catalog/Clinical+and+Interpretive/83142
It's under the interpretations subtitle. Thank you very much.
It's under the interpretations subtitle. Thank you very much.
Please provide the link to your reference. So we all can see what your looking at.
My antibody test was given at 13 weeks and the PCR at 14 weeks. This is very concerning to me. I don't know why the Mayo clinic would say that those results should not be considered equivalent to an "undetected" result?? I am so confused.
Thank you, I have been relaxing about this whole thing until my husband came across this on the mayo clinic website, and I am so anxious again. Can those of you who are knowledgeable, please advise? This is what he found on Mayo Clinic:
A result of "<15 IU/mL (<1.18 log IU/mL)" indicates that HCV RNA is detected, but the HCV RNA level present cannot be quantified accurately below this lower limit of quantification of this assay. When clinically indicated, follow-up testing with this assay is recommended in 1 to 2 months. To assess response-guided therapy eligibility, an "Undetected" result is required, and a result of "<15 IU/mL mL (<1.18 log IU/mL)" should not be considered equivalent to an "Undetected" result.
My results say: <15 HCV RNA, Quantitative Real Time PCR IU/mL
<1.18 HCV RNA, Quantitative Real Time PCR Log IU/mL
HCV RNA Not detected. Reference range ,15 IU/mL and <1.18 Log IU/mL. This test was performed using the COBAS (R) AmpliPrep/COBAS/ (R) RaqMAn (R) HCV Test, v2.0
I was feeling very relieved that with my low antibody score of 1.04 and it saying "undetected" I was pretty much in the clear, but now I am confused by this statement on the Mayo Clinic website.
Please give me your educated opinions on this, it seems contradictory and that it found the virus, but it is low enough that it can't quantify or measure it?
I apologize for being so anxious about this, I am on an emotional roller coaster over this whole thing. I really appreciate all of your help.
A result of "<15 IU/mL (<1.18 log IU/mL)" indicates that HCV RNA is detected, but the HCV RNA level present cannot be quantified accurately below this lower limit of quantification of this assay. When clinically indicated, follow-up testing with this assay is recommended in 1 to 2 months. To assess response-guided therapy eligibility, an "Undetected" result is required, and a result of "<15 IU/mL mL (<1.18 log IU/mL)" should not be considered equivalent to an "Undetected" result.
My results say: <15 HCV RNA, Quantitative Real Time PCR IU/mL
<1.18 HCV RNA, Quantitative Real Time PCR Log IU/mL
HCV RNA Not detected. Reference range ,15 IU/mL and <1.18 Log IU/mL. This test was performed using the COBAS (R) AmpliPrep/COBAS/ (R) RaqMAn (R) HCV Test, v2.0
I was feeling very relieved that with my low antibody score of 1.04 and it saying "undetected" I was pretty much in the clear, but now I am confused by this statement on the Mayo Clinic website.
Please give me your educated opinions on this, it seems contradictory and that it found the virus, but it is low enough that it can't quantify or measure it?
I apologize for being so anxious about this, I am on an emotional roller coaster over this whole thing. I really appreciate all of your help.
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Question 2. What do these test results mean: “<15 Detected” or “<15 Not Detected”?
A “<15 Detected” means the assay was able to detect HCV RNA but was not able to accurately quantitate the viral load. A “<15 Not Detected” means the assay did not detect HCV RNA (Target Not Detected).This test is performed using the COBAS® AmpliPrep/COBAS® Taqman® HCV Test v2.0. The lowest viral load this assay can accurately quantify is 15 IU/mL, but the limit of detection is 10-13 IU/mL. Therefore, we can qualitatively report detection even if the viral load is under 15 IU/mL.
http://education.questdiagnostics.com/faq/FAQ22v1