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Positive HSV 1+2 Combined IgG Test

Hello

About nine months ago, I got involved with someone who later revealed that he had a bit of a 'promiscuous' past. A few weeks after we last had sex, I got a really bad blister rash just under my bum, high up on the back of my thigh. I went to see a doctor and he prescribed some medication (I forget the name) saying that the rash was caused by a resurfacing reaction from former chicken pox. (Let me note that this was in a third world country at a free clinic, so no testing was offered, and I was travelling at the time and so I could not follow up with testing). Anyway, the medication cured the blisters after about a week. I did some research on the medication and it is also used to control Herpes Simplex flare ups.

Last week, I had a Herpes test done (six months after the blister rash) and the results were presented as follows:

IgG anti HSV 1+2: ..........  Positive: Index 14
IgM ant HSV 1+2: ........... Negative: Index 7

Usual values:               Negative:   Index  11

This test was also done in a developing country. Now, I have read that if the test is combined, then it is pretty much useless, but can I infer that I have either Herpes 1 or 2 or both from these results? The test is a little pricey, so is it worth me trying to find out if I can get another test done and specifically ask them to split the results, if at all they can?

I am trying to stay as calm as possible, but given all this information, should I be worried?

Any guidance would be much appreciated.

Thank you.
Best Answer
3149845 tn?1506627771
Hi. im not sure what test you had as the numbers are not familar to me. Most herpes type specific test start at positive 1 and usually stop at 5. If your combined test show slightly over positive it would fall into the false positive range so you would need retesting anyway. Dont be overly concerned and have a herpes select type specific.

By the way, the original rash that you describe, if it were herpes from chickenpox is called shingles and this is for those older people most often and usually only occures once in a life time and can be very very painful. If your a young person i really doubt it was shingles. Did you have the chicken pox vaccine at youth?
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Avatar universal
Okay. I will see if I can get a biokit done somewhere.

Thanks again for the patience and the help and advice.

Kindest regards.
Helpful - 0
3149845 tn?1506627771
im not sure about the WB but i believe the biokit is available.
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Avatar universal
Okay, thank you for all the help Life360. I understand that nothing is absolutely certain with these things.

I suppose I will have to seek further confirmation somehow. I wonder whether you are aware of Biokits or the Western Blot being available in the UK? I will be travelling there and I think that may be my only opportunity to get any further confirmation.

Thank you.
Helpful - 0
3149845 tn?1506627771
They should be much higher but thats not written in stone. There is a range for a reason any anywhere in that range could be confirmed positive.
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Avatar universal
Yes, the second set of results should read HSV 2. And haven't had any sexual contact (sex or kissing) for over six months. Is it not possible for a result to be such a low positive six months after exposure?
Helpful - 0
3149845 tn?1506627771
Hi again, its only  mentioning hsv1 not hsv2 unless there is a type error on the second one. Low positive are indicative of a false positive or a recently acquired infection if taken prior to 3 months post exposure.
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Avatar universal
Dear Life360

I note that you are currently active. Any thoughts?

Thank you.
Helpful - 0
Avatar universal
Hello again

I managed to find a lab which does Hepres Type Selective testing and my results were as follows:

Technique         ELISA

IgG HSV 1: ..........  Positive: Index 13
IgM HSV 1: ........... Negative: Index 4

IgG HSV 1: ..........  Positive: Index 14
IgM HSV 1: ........... Negative: Index 3

Usual values:     Negative:    Index under 9
                        Equivocal:  9-11
                        Positive:     Index over 11

Should I take this as confirmation that I am positive for both Types 1 and 2 herpes, or are the low values still cause for doubt?

And I don't know why the results are reported as whole numbers rather than ranging from 0-5 with decimal points...

Please someone respond with whatever thoughts you may have because it's all I can do to keep from losing my mind right now. I am considering lifelong celibacy as I can't imagine admitting to anyone that I have herpes, and I certainly don't want to infect anyone else :(

Thank you in advance.

PS. Does anyone know if Biokits and/or Western Blot are available in London, UK?
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Avatar universal
Oh, I just looked at the results again and it actually says the ELISA technique was used.

Thank you.
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Avatar universal
Thank you for your response, Life360. I thought the test used was the usual IgG Test, but with the numbers multiplied by 10 for whatever reason. Are you suggesting this isn't a fair assumption to make? But if you think it is a low positive, and could therefore be a false positive, then I will see if I can get a Select Type specific test done...

I am 25 years old. So if you are suggesting it wasn't shingles, then does that mean it was most likely actually a herpes flare up? I realise it's not possible to conclude that without testing on the lesions having been performed, but in your opinion based on the description given. And it was pretty painful. I could barely sit and had to limp slightly when I walked. Is it possible for a herpes flare up to manifest in that area?

Thank you, once again.
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Avatar universal
I really don't know why that keeps happening!

Negative:    Index under 9
Equivocal:  9-11
Positive:     Index over 11
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Avatar universal
Sorry, the rest of the results got truncated for some reason... The should be completed as follows:

Usual values:               Negative:   Index 11
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