Oh yes! Anxiety, severe depression, insomnia, extreme irritability, memory loss, couldn't think or concentrate, no energy or desire to do anything or see anyone, etc. Your ovaries may have been negatively affected due to loss of blood flow and feedback with the uterus. The uterus also seems to play a role in mood to some degree. Quite a few women with whom I've connected complained of changes in mood or affect after their hysterectomies despite no classic menopausal symptoms. However, some women in natural menopause have anxiety.
There are some supplements that may help. Your local health food store would may be a good resource. If you are concerned about breast cancer, studies show that taking estrogen does not increase risk.