To clarify that, let me explain. I suffer from hemi-crania continua, which is an indomethician reactive migraine. I have been taking that medication for a year and a half. For the sensations and pain that I feel during those migraines specifically, I take the pill and within half an hour I have relief. Most of the time remission for up to 16 hours. If taken 2 x daily I do not feel those specific sensations and pained throbbings except on rare occasions that i have a rough day. Or it gets irritated by its partner in crime. As such, I also experience a second set of migraines that do not react to the indomethicin. These are far different in type of pain and how they effect my ability to stay functional. Both are equally debilitating, however the other will not succumb to pain medication. Neither will react to any over the counter medication, ie bayer, advil, excedrin, and so on. Nor will they budge with such medications hospitals can administer, ie oxycodone, vicadin, morphine, vollum. As of this day that i write this post, i have had a continous migraine for around 260 some days. My neurologist has tried botox, it worked the first time. Second time not so much so they increased the dosage, third time worked less than the second. My primary has already said he can do nothing else for me. Neither have said anything concrete about what to do next. Beta blockers are out of the question, I am suseptible to dispnia, a side effect of 1%. I routinely take three anti migraine medications daily, not counting the pain pill indomethician. I have yet to get back to me neurologist this last two months. Two of the more drastic measures for someone in my position is not something I care to think about right now. I am hoping to find a suggestion from someone else that I can then research for myself to see if it can be applicable to my problem.