Juxacortical Junction

[joy496]

Just need some help! What does a few focal regions of increased MR signal at the juxtacortical gray-white junction mean? Can vasculitis secondary to migraine cause this? In addition, what is increased T1 and T2 signal changes identified in multiple levels of the thpracic spine most compatible with hemangiomas involving T12,T9, and the T5 vertebral bodies. Smaller hemangiomas questioned at T8 and T7 versus focal fat. I don't understand this and could really use some knowledge. I have been having symptoms of weakness, tingling throughout my body, dizziness, loss of balance mostly when standing still, urinary retension and frequency, heat intolerance, etc for  some time. Could use some advice. Thanks.

[Quixotic1]

These are bony, vertebral lesions.  They are often little clusters of blood vessels called hemangiomas,  which are usually just watched (though I can't really know in your case).  Anyhoo, they have nothing to do with MS or the spinal cord.

You should ask your doc about them.  If they are a problem they would likely be handled by a back specialist or a neurosurgeon.

Quix

[joy496]

They are in the vertebral bodies.

[Quixotic1]

It depends on whether the increased signals (areas of abnormality or lesions) are in the cord or in the bony spine.

Quix

[joy496]

What does it mean to have increased T1 and T2 signal changes in multiple levels of the thoracic spine.

[joy496]

Thanks for your infomation and reply. Sorry for the all caps.

[Quixotic1]

Hi, Welcome back!  

You have some interesting news.  Your MRI is now showing some lesions.  Lesions at the Juxtacortical Junction are particularly characteristic of MS, according to a couple of the MRI sites I've read.   One of them is the Radiology Assistant from the Netherlands, which is written by one of the most prominent doctors in MS and MRIs.  So new lesions in a place that suggests MS.

The numbness and tingling "all over" is unusual for MS, as it tends to be here and there, but not everywhere.  The leg stiffness, poor tandem gait, easy muscle fatigue, and weakness of the voice can be seen in MS, but I hope they also check you for a disease called Myasthenia Gravis.  I'm glad you're getting into to see an MS Specialist.   He should be doing the rule out of other neurological diseases, too.

Do you need us to write our answers in ALL CAPS?  If not, would you use normal lettering so it is easier to read?  Many of us find all caps more difficult to track and read, but we do use them for people with limited site.

Quix

[joy496]

WHAT DOES IT MEAN TO HAVE MULTIPLE RESTRICTION BANDS IN THE CSF ALSO PRESENT IN THE SERUM. UNABLE TO DEFINE WHETHER THESE ARE OF SYSTEMIC OR INTRACEREBBRAL ORIGIN. MYELIN BASIC PRITEIN IS NEGATIVE. FIRST MRI 7 YEARS AGO NEGATIVE. NEW MRI 6 MONTHS AGO SHOWS A FEW FOCAL REGIONS PF INCREASED MR SIGNAL BILATERALLY AT THE FUXTACIRTICAL GRAY-WHITE FUNCTION. GAIT IS NORMAL AND TANDUM GAIT IS IMPAIRED. HAVE NUMBNESS AND TINGLING ALL OVER, DIZZINESS,PAIN OF THE EXTREMITIES WORSE TO THE LEGS, MEMORY LOSS, FORGET WORDS, FLIP NUMBERS ALOT,STIFFNESS IN LEGS ESP WHEN FIRST GET UP, EAR PAIN THAT COMES AND GOES, WILL LOSE MY VOICE IN THE MIDDLE OF A SENTENCE THAT COMES AND GOES, WHILE TALKING MY VOICE WILL GET WEAK LIKE I GET SHORT OF BREATH, MY MUSCLES BECOME VERY WEAK WHEN I USE THEM LIKE HOLDING MY GRANDBABY OR JUST PHYSICALLY PLAYING WITH THEM FOR JUST A FEW MINUTES, ECT. APPT SCHEDULED TO SEE AN MS SPECIALIST SOON.

[joy496]

essdipity

I would like to thank you for responding to my questions. Just want you to know how much your reply has helped me. I feel so tired at times, just fighting to reach an answer. It is just nice to have a person to speak to about this. I will see my neuro doc Friday and plan to discuss my test results.

Joy