Hi:) I'm not aware of the others but I know for a fact methadone is NOT safe for pregnancy. I have a friend of a friend that was on methadone while pregnant because she was addicted to Vicodin and other drugs. They gave her methadone to ween her off. I can tell you while she was taking this, she was pregnant and her baby was born with A LOT of issues. He was born with a hole in the rough of his mouth, he is 3 and still cannot walk or talk. It's a sad sad situation and the quicker you can get your sister the help she needs, the better for that baby's outcome. One question why is she on methadone?
I don't see how they would be safe. I'm not a doctor but it's to be known that taking medication during pregnancy is not "really" safe. I think she should get a second opinion from a doctor, this is my advice. Hope it helps.