My plam has tiny holes in the creases of his palms and fingers line then there make a red mark and start pain, These little holes will get hardened white tissue in them which he pulls out leaving again a little tiny hole. These holes are in every crease and fold of his palm and fingers which is a cause of embarassment for him. A couple of times it is if the holes have gotten infected under the hardened area but as soon as the protrusion is pulled out the area increased day by day.