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TSH over 550 (Hypothyroidism). Anybody with related case?

Hi all,
I had TSH level 453.2 the first time and over 500 the second time. Doctors and  my biology teachers were astounded looking at the fact i don't feel any symptoms. I dont know what to conclude, my teacher says i probably have a mutation. My dad has thyroid; probably genetic. But According to my prof, i should not be alive. Now i am on 100 mg levothyroxine medication. Anybody with related case?

PS: I am 20 male.  
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Avatar universal
I just noticed you started a thread of your own, so I will no longer respond to this thread.  
Helpful - 0
Avatar universal
Di your doctor start you on the full 200 mcg?   When did you start?  Have you had any reaction to that dose all at once?  Were you tested for the biologically active thyroid hormones, Free T4 and Free T3, or just TSH?  What symptoms did you have?
Helpful - 0
1 Comments
I was recommended 300 mcg of thyroxine. I tiok for 2 days but the 3rd day i had palpitations and irregular heart beat. So i came down to 200.
I have severe fatigue, bone pain, thinning of hair, weight gain.
Avatar universal
I am 33 years old females TSH levels are 570. I have typical hypothyroid symptoms and low t3 t4. I have extreme fatigue and have started thyroxine 200 mcg.
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Avatar universal
Then it was figured out that even though tsh was very Hugh my t3 and t4 were in single digit.I take levothyroxine now.doctor had no clue when thy saw it
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Avatar universal
Be aware that TSH causes NO symptoms in and of itself.  TSH is nothing but a signal from the pituitary to the thyroid to tell it to produce more T4.  It's low FT4 and FT3 levels that cause symptoms.

Adrenals often do take over and try to compensate for inadequate thyroid hormones (in adults as well).  The problem is that the adrenals often burn out doing that (adrenal fatigue), and adrenal insufficiency often wreaks havoc with taking thyroid meds.  The adrenal problem usually has to be addressed first.    
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Avatar universal
I believe I read somewhere that the younger you are the less symptomatic you may be even with elevated TSH. Especially if it is in the early stages.

From what I remember it has to with the thyroid being able to withstand the TSH signal better in younger individuals and that their adrenal response may be making up for any decrease that may be initially evident…. Basically the younger you are the more the rest of your body can compensate. Although, I’m guessing with a level that high, that compensation will be short lived!
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Avatar universal
My daughter, who was 12 at the time and is now 14, had a TSH of over 500 with no symptoms. She was referred to a pediatric endochronoligist, who verified the level with an ultrasound, which showed that her thyroid had pretty well just become dead tissue. (There is a history of thyroid disease on both sides of her family.)
Helpful - 0
Avatar universal
Let us know what you find out about your FT3 and FT4.  Good luck...
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Avatar universal
This whole thing so bizarre. I will surely get my free T3 and T4 done. Thanks everyone
Helpful - 0
Avatar universal
They did it twice. :/ But yeah i show no symptoms.
Helpful - 0
Avatar universal
Just a thyroid ultrasound! :/ Is there anything else i should look into?
Helpful - 0
1 Comments
My tsh level was vry high at 612
Avatar universal
A TSH that high, with no symptoms, is very unusual.  I agree that you should have FREE T3 and FREE T4 tested immediately.  Be sure to request FREE since there are also total T3 and total T4 tests that are not nearly as useful.  TSH can be affected by any number of variables in the thyroid/hypothalamus/pituitary axis.  So, it is at best a screening tool to be considered only after FT3, FT4 and symptoms are evaluated.  
Helpful - 0
1756321 tn?1547095325
From Thyroid Australia - "The level of TSH can be elevated several hundred fold in severe primary hypothyroidism." I've never heard of severe primary hypothyroidism with no symptoms.  Free T3 and free T4 should be ordered at the very least along with the TSH.

Causes of falsely high TSH include laboratory technical problems, especially with the washing step; any interfering substance eg: heterophilic antibodies, human anti-mouse antibody (HAMA); macro TSH (TSH of high molecular weight).
Helpful - 0
929504 tn?1332585934
I've seen other posts in the past from others whose TSH was very high (around 300). It can be very dangerous if left untreated due to the fact that this indicates hypothyroidism. We all need our thyroid hormone to survive, whether it's by the funtioning Thyroid Gland or through Thyroid Hormone med's. Have you had any other thyroid labs done??
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