Aa
Aa
A
A
A
Close
Avatar universal

Bones and heart

So the reason the doc is worried about my tsh being .038 is because of heart and bones but everything I read states that undermedicated not overmedicated can cause more damage to heart and bones plus I have no signs or symptoms of overmedicating. I seriously need some really good articles to show doc, they will not listen.
Best Answer
8846197 tn?1400504226
MEDICAL PROFESSIONAL
Too little thyroid can cause osteoporosis.  If on very high doses of thyroid (TSH < 0.01), if a patient takes at least 1500 mg of calcium per day, they do not get thinning of bones  *American Thyroid Association 2014 Annual Conference).  On contrary, I see bone density get thicker on thyroid medication.  You asked for an article, here is one the best ones:

Lancet. 1992 Jul 4;340(8810):9-13.

Long-term thyroxine treatment and bone mineral density.

Franklyn JA1, Betteridge J, Daykin J, Holder R, Oates GD, Parle JV, Lilley J, Heath DA, Sheppard MC.

Abstract

Studies of the effect of thyroxine replacement therapy on bone mineral density have given conflicting results; the reductions in bone mass reported by some have prompted recommendations that prescribed doses of thyroxine should be reduced. We have examined the effect of long-term thyroxine treatment in a large homogeneous group of patients; all had undergone thyroidectomy for differentiated thyroid cancer but had no history of other thyroid disorders. The 49 patients were matched with controls for age, sex, menopausal status, body mass index, smoking history, and calcium intake score; in all subjects bone mineral density at several femoral and vertebral sites was measured by dual-energy X-ray absorptiometry. Despite long-term thyroxine therapy (mean duration 7.9 [range 1-19] years) at doses (mean 191 [SD 50] micrograms/day) that resulted in higher serum thyroxine and lower serum thyrotropin concentrations than in the controls, the patients showed no evidence of lower bone mineral density than the controls at any site. Nor was bone mineral density correlated with dose, duration of therapy, or cumulative intake, or with tests of thyroid function. There was a decrease in bone density with age in both groups. We suggest that thyroxine alone does not have a significant effect on bone mineral density and hence on risk of osteoporotic fractures.
4 Responses
Sort by: Helpful Oldest Newest
649848 tn?1534633700
COMMUNITY LEADER
"Normal" isn't the same for all of us, but as long as neither are over range, you should be fine.  You're only hyper (over medicated) if you have hyper symptoms.
Helpful - 0
Avatar universal
ft3 and ft4 are in normal range
Helpful - 0
649848 tn?1534633700
COMMUNITY LEADER
Those with increased FT3 (which is the active thyroid hormone) levels, may have increased bone loss, but it's not because of the increased FT3; it's because of increased metabolism, resulting from adequate thyroid hormones.  
Helpful - 0
Have an Answer?

You are reading content posted in the Thyroid Disorders Community

Top Thyroid Answerers
649848 tn?1534633700
FL
Avatar universal
MI
1756321 tn?1547095325
Queensland, Australia
Learn About Top Answerers
Didn't find the answer you were looking for?
Ask a question
Popular Resources
We tapped the CDC for information on what you need to know about radiation exposure
Endocrinologist Mark Lupo, MD, answers 10 questions about thyroid disorders and how to treat them
A list of national and international resources and hotlines to help connect you to needed health and medical services.
Herpes sores blister, then burst, scab and heal.
Herpes spreads by oral, vaginal and anal sex.
STIs are the most common cause of genital sores.