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Can TPO ever fluctuate??

Hello- Please help.  I'm so confused.  I'm 48 years old, have exercised all my life, ate healthy. Can the thyroid's TPO test show high because the thryroid was compromised due to dental problems?  What I'm trying to ask is can the thryoid bounce back from a high TPO result? For 6 months I went to a dentist, dental surgeon, endodontist, and finally a periodontist to find out what exactly was wrong with my constant pain in my tooth.  After numerous root canals and antibiotic, about 10 in those 6 months the periodontist told me what was wrong.  Keep in mind I floss and brush regularly....
After this ordeal which was stressful and with all the antibiotics I was on now I'm showing signs of hypothyroidism.  Can my thyroid bounce back after a month or two and become better by itself???
I really don't want to take synthroid for the rest of my life if I don't have too.
I'm 128lbs (same as high school), 5'5" walk/run 20 miles a week and very active.  I have no signs of hypo other then tired with 4 children.  My hair and skin is healthy also.
I'm really scared and don't know who to turn too.  My doctor said I have to take the medicine or I'll be sick.  She won't listen to me and won't think of Armour.  I was to get my adrenal glands checked and my progesterone checked but she isn't calling.  If feel so lost.  I know two people on synthroid and they can't even walk 1 mile, can't lose weight and have hair loss....
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Avatar universal
As an aside to my last reply, I thought taking synthroid makes your thyroid inactive and not function on its own.  I'm kind of confused.
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Avatar universal
Thank you for your replies.  What do you think about seeing an endocrinologist. They both said the same Dr. and she is credited.
Is the FT3 and RT3 ratio a 13.4???  I was doing some research and think I may have figured out what the ratio should be.  It said around 18-20 and if I figured mine out it's low.
Does this mean I need the T3 supplement and the T4 supplement?
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Avatar universal
Hi again.

Since your previous labs, TSH has gone from 4.68 up to 5.05...not a big jump, but higher nevertheless.

FT4 has stayed absoluely the same, but it's a bit on the low side, in the bottom quarter of the range (midrange is the rule of thumb).  FT3 is in the bottom third of the range (upper half to third is recommended).  Antibodies have not changed, which is to be expected, especially when they report as "greater-than 600" rather than giving an actual count.

Your two doctors are basically on the two sides of this argument of "when to start treating Hashi's".  The first recognized the Hashi's and wants to treat before you develop symptoms.  The second sees your labs as "normal" (they are, except for TSH, but low), so doesn't think it's worth starting to treat now.  However, he's also saying that the antibodies might spontaneously resolve, which makes me think he doesn't know a lot about thyroid.

Most of us didn't have the luxury of being diagnosed early enough for this to have been a consideration for us.   However, if I were in your position, I think I'd be tempted to start treatment (very unlikely with your low range labs that you'll go hyper).  You might avoid a lot of very unpleasant symptoms and support your thyroid so that some of the physical thyroid manifestations of Hashi's are minimized (like nodules and swelling).

Looking back over your second opinion's statements, I don't think this guy is someone I'd trust.  If you're still on the fence about what to do...maybe a third opinion?
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Avatar universal
Hi I hope I have the right tests now.
TSH                                           5.05
Triiodothyronine, Free Serum       2.7 pg/ml           ref 2.0-4.4
Reverse T3                               201 pg/ml           ref 90-350
TPO                                         600 IU/ml           <35
Vit D                                         37.4                    32.0-100.0
Cortisol                                      8.6 ug/dl             2.3-19.4
T4                                             1.05 ng/dl            .82-1.77
Thanks for your input.  I'm not sure what the ratio of the Rt3 and T3 should be.

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Avatar universal
Yes I will ask the Dr.tomorrow.  I have an order for TSH/FT4 but not FT3.  I will ask for the FT3 because of the importance of knowing the ratio of the RT3 vs the FT3.
My progesterone was 0.8.  Not sure if that matters.
Thanks again! I'll reply when the results of the tests are here.
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Avatar universal
See if you can get them to test FT3 as well.  I noticed that they tested RT3, which is good, but the really important thing with RT3 is the ratio of FT3 to RT3.  So, RT3 is a bit useless without FT3.  It's too bad to waste a perfectly good opportunity to check out your FT3/RT3 ratio.
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