I know definately that the depression can be caused by the thyroid disease. Ive had it for 17 years. Yes, definately get her levels tested. They fluctuate just like a diabetic, but not as often. I have to get my levels tested every three months because my levels for some unknown reason, go up and down and I take my meds on an empty stomach faithfully every day. My first thought was the medication. Levothyroxine is the generic brand of synthroid. Some people get side effects from generic medication. I don't know who much of this is true, but that's what I've heard. Also, they need to check on other meds that she is on to see if one is counteracting with the other. Since having this disease for 17 years, Ive had extremely dry skin, and my skin has gotten pailer over the years. I was dark and now am about three shades lighter. I can tell you it has not been easy with this disease. Insomnia is a big one and the depression and weight gain. She has to try to get some control. Its not easy. Im thinking her levels are off because as soon as I forget a dose, I am crying uncontrollably and can't stop. I also begin headaches and nausea. but, I can't eat when its off. I lose weight. People are different. Hope this helps some. Good luck.
Hypothyroidism can cause Psoriasis among other things. A dermatoligist can help with this. I have both and use some topical medications which have worked for me.
I'm not sure what amount of testing you can get through the ER, but somehow, somewhere, I would get her tested for FT3, FT4 (not total T3 and total T4), along with TSH, and the thyroid antibodies, TPO ab and TG ab.