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High TgAb+Thyroglobulin,IMA orRIA and Thyroid Peroxidase (TPO) Ab
During a recent routine physical blood test my TgAb+Thyroglobulin,IMA or RIA reading was measured at 1251.3 and my Thyroid Peroxidase (TPO) Ab measured 482. My Doctor prescribed 25MCG of LEVOTHYROXINE, although I feel fine. I was wondering what might be the cause of these high readings and are there any alternatives to medication.
Best Answer
Were you also tested for the active thyroid hormones, Free T4 and Free T3? If so, please post results and reference ranges shown on the lab report. Even more important, what symptoms do you have, if any?
1 Comments
My (T4) number is 6.3 with a Reference Interval of 4.5-12.0 and my (T3) number is 139 with a Reference Interval of 71-180. No mention of the word “Free.” My TSH is also high 6.160 with a Reference Interval of 0.450-4.500. Also I have no symptoms beyond a weight of 300 pounds gained mostly over the past 10-15 years which I don’t feel is reflective of my eating habits or activity level.
Your T4 and T3 results are Total T4 and Total T3. Only a small portion of each of those is free of TBG and thus active. Those small portions are called Free T4 and Free T3. Those should always be the ones tested. Free T3 is the biologically active thyroid hormone that largely regulates metabolism.
Your Total T4 is at 24% of its range. Your Total T3 is at 62% of its range. If we assumed that the Totals are representative of the Frees, then it appears that your body is converting extra T4 toT3 in an effort to maintain adequate T3 levels. But you really need to know your FT4 and FT3 to get a better assessment. In addition, Vitamin D affects the response to thyroid, so you need to tet for that. It should be at least 50 ng/ml. B12 is also important. It should be in the upper part of its range. Ferritin is also very important. It is a storage form of iron and should be at least 100. If you are deficient in either of these three you can supplement to optimize.
Even more important than lab tests is an evaluation for symptoms typical of hypothyroidism. Please review the following list and tell us if you have any of these.
Fatigue
Increased sensitivity to cold
Constipation
Dry skin
Weight gain
Puffy face
Hoarseness
Muscle weakness
Elevated blood cholesterol level
Muscle aches, tenderness and stiffness
Pain, stiffness or swelling in your joints
Heavier than normal or irregular menstrual periods
Thinning hair
Slowed heart rate
Depression
Impaired memory
Enlarged thyroid gland (goiter)
There is more to discuss, but first please respond to this post.
Your Total T4 is at 24% of its range. Your Total T3 is at 62% of its range. If we assumed that the Totals are representative of the Frees, then it appears that your body is converting extra T4 toT3 in an effort to maintain adequate T3 levels. But you really need to know your FT4 and FT3 to get a better assessment. In addition, Vitamin D affects the response to thyroid, so you need to tet for that. It should be at least 50 ng/ml. B12 is also important. It should be in the upper part of its range. Ferritin is also very important. It is a storage form of iron and should be at least 100. If you are deficient in either of these three you can supplement to optimize.
Even more important than lab tests is an evaluation for symptoms typical of hypothyroidism. Please review the following list and tell us if you have any of these.
Fatigue
Increased sensitivity to cold
Constipation
Dry skin
Weight gain
Puffy face
Hoarseness
Muscle weakness
Elevated blood cholesterol level
Muscle aches, tenderness and stiffness
Pain, stiffness or swelling in your joints
Heavier than normal or irregular menstrual periods
Thinning hair
Slowed heart rate
Depression
Impaired memory
Enlarged thyroid gland (goiter)
There is more to discuss, but first please respond to this post.
1 Comments
The weight gain is the only symptom. I recently visited a Nutritionist who has helped me lose about 10 pounds over the last 3-4 weeks by greatly reducing carbohydrates. Other than that I feel well. Thank You very much for your help.
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