I would really appreciate it if someone could give me some guidance/ their opinions on this! I am a 33-yr-old female. A couple years ago I began presenting with some symptoms of hyperthyroidism, mainly heart palps, very increased heart rate and sweating. In testing my thyroid at that time, my TSH was in the low range (.7) but normal according to lab values. Just two weeks later, I was undergoing blood testing for a different matter at the Mayo Clinic, and they drew my blood to discover my TSH was now 17.3.
After that time, my TSH ping-ponged back and forth, usually falling at around 4 or 5. My doctors 'watched' me as I was subclinical hypothyroid and I was not symptomatic. During this time though, I was tested multiple times for TSI and TPO antibodies. TPO was always negative, but my TSI were occasionally high... sometimes around 120-125 (normal range), other times as high as 175. I also had a thyroid scan which showed increases blood flow to the thyroid in a pattern suggestive of Hashi's (not Graves).
When I became pregnant recently, I was put on Synthroid. I'm now currently stable at around 2, with higher-end normal T3/ T4 values.
My question: is it possible to be hypothyroid with TSI antibodies? Do I have Hashi's, Grave's or both... and why aren't TPO antibodies showing up if I indeed do have Hashi's?
Would really appreciate a response. My endocrinologists seem stumped... or at least, they haven't been able to adequately explain this matter or suggest further tests.
Thanks!