Need some help with lab results and physical/mental symptoms

[Elleon22]

Hi,

For the past month or so I've been having issues that I have never really experienced before. I have been having anxiety, depressive episodes, racing thoughts, insomnia, night sweats, high heart rate, exercise intolerance, weight loss with normal food intake, chest tightness, and stomach issues.

The few months prior to this I had some fatigue issues and small amounts of anxiety but it is winter here so that's nothing too new. I'm currently being prescribed wellbutrin which has been keeping my mood level as well as helping to curb some of the other mental symptoms. I also have abilify and klonopin which I haven't used yet.

So, my initial lab results indicated a low tsh, highish free t3, and high free t4:
Tsh .42 ref .4-4.2 mU/L
Ft3 6.2 ref 3.7-6.9 pmol/L
Ft3 26.5 ref 9.7-25.7 pmol/L

My latest labs came back lower but still a bit elevated. It seems some t4 was converted to t3 as well:
Tsh .72 (taken at night)
Ft3 6.51
Ft4 24.4

The other test that I was able to have done was anti-tpo which came back as:
89 ref 0-34 IU/mom
I could not get done tbg or tsi.

Now the symptoms have been getting better but some are still persisting. Just wanted to get some opinions on what could be going on.

Thanks in advance.

[gimel]

Your TPO ab test is indicative of having a thyroid autoimmune disorder, called Hashimoto's Thyroiditis.  With Hashi's the autoimmune system erroneously identifies the thyroid gland as foreign to the body and produces antibodies to attack and eventually destroy the gland.   Frequently during the early stages, the person will go into a hyper stage and later into hypothyroidism.  Your  symptoms and lab results are indicative of being hyper.  

One way to find out more about what is going on would be to do an ultrasound of the  thyroid gland to see if there are any nodules present.  Nodules can leak thyroid hormone faster than normal and cause hyper symptoms due to the higher levels of Free T3 and Free T4.   Also, in view of her symptoms, I would also insist on a TSI test just to be sure that Graves' Disease is not present also.  

What did the doctor have to say about all those symptoms and the high levels of Free T3 and Free T4?

[Elleon22]

Thanks for replying. The doctor I usually see at my regular clinic wanted to monitor my thyroid levels after the initial testing. The most recent test was done in the ER but the doctor there was not very helpful to say the least (especially after a 15 hour wait). He said it wasn't likely to be causing any of my symptoms...yeah right. I saw another doctor at my usual clinic who is running it by an endocrinologist due to the abnormal tpo. I will find out in the next few days.

I was suspecting either graves or hashimotos. Hashimotos runs in the family and I have had periods of unexplainable fatigue over the years which may make sense now.

Let me know if you need any other information.

[gimel]

Since hypo patients are frequently too low in the ranges for Vitamin D, B12 and ferritin, it would be good to test those as well.

[Elleon22]

My B12 is sky high at 1400 (ref 400-900 I believe). Ferritin was upper middle range and I'm still waiting on vitamin d from a few months back now. Extremely popular test in Canada now.