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graves disease

I just had labs done and here are the results
TSH 0.16 (0.45-4.5)
TSI 101   (0-129)
FT4 0.67 (0.6-1.30)
FT3 2.5  (2.3-4.3)
TT3  94  (79-149)
Anti thyroglobulin 51 <100
Anti-TPO 9 <10
TBII 31% <16% H
I am taking 5 mgs of MMI along with 25mcgs of levoxyl daily. Should I change my dose?
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Avatar universal
The doctors I just saw recommend staying on MMI until all antibodies are gone.

My problem is I'll be in a coma if I don't take levoxyl along with the MMI because I respond too fast to the MMI.

My TSH has not returned at all in 2.8 years. Sometimes this does happen to people who have Graves for a long time. I probably had it much longer than 2006.

Anyway, I'm still feeling sick all the time. I have no energy and all the symptoms of hypo except for the TSH.

I hope Dr. Mark gets back to me with some thoughts.

My husband is a saint to live with me. It's a good thing my kids are both married with kids because they wouldn't be having much fun living home right now. Thanks again for writng.
Helpful - 0
213044 tn?1236527460
I think you have Grave's that has gone into remission.

You do not have Hashimoto's.

I think there is another problem going on as well, or your TSH would be high. Also, if you have Grave's and it is in remission, you should not need the Methimazole OR the Levoxyl.

If your Grave's is in remission your T4/T3 should be in a normal range. They are within "lab limits", but you are hypothyroid.

Something else is going on. I hope the new doctor figures it out.
Helpful - 0
Avatar universal
I just went to a new doctor. I saw 2 doctors(endos) they said continue taking these meds and test in 6 weeks. They also agreed that my tests really don't fit Graves disease anymore. WHAT IS WRONG WITH ME? I had my cortisol tested in August and it was normal 17 after a fast. Maybe it's piuitary related. All I know is I don't feel well at all.
Thanks.
Helpful - 0
213044 tn?1236527460
Your TPOab is below limit, your TGab is below limit, your TSI is below limit.

The only antibody you have not listed is TRab and TBI. You may have a high TRab, which is the only blocking antibody.

You are not getting proper treatment. You should not be on Methimazole now, although when you were first diagnosed it was  needed. You need a higher dose of Levoxyl, tests to find out why your TSH is low when your thyroid hormones are low, and most of all, a new doctor.

If a retired carpenter from the sticks can see the contradictions in your blood tests, any competant doctor should be able to see there is a problem.

Don't stop taking your meds because of anything I have posted.

Get a second opinion because of everything I have posted.

Adrenal tests and pituitary tests.
Find another doctor.
Helpful - 0
Avatar universal
Hi there,

I was dx'd with Graves in March 2006. I have been on MMI(methimazole) for 2.8 yrs. I started off on 30 mgs. and went very very hypo right away. I have gained 38 pounds in 2.8 years and feel dreadful. When dx'd my TSI was 243 <129. My FT4 for was 1.86(.8-1.85) and FT3 was 2.60 <2.00. I really never had very  high FT's. They have always stayed low  but my TSH has been low forever. I think I have many blocking antibodies because of my TBII is 31% <16%.
Can someone have Hashimoto Disease and have a high TSI? I feel so much more hypo than hyper and have since being diagnosed with Graves. I have seen 3 different endos during the past 3 years and no one seems to help me. They all want to treat my TSH while my FT's are in the tank. I quit going to the first one because she wanted me to take too much MMI and I felt horrible. I still feel awful. I'm tired all the time, weight gain is out of control, now I have nausea and GERD...that's new along with higher BP than usual. I feel positively dreaful and I'm so depressed I don't know where to turn.
Thanks for answering and trying to help me.
Helpful - 0
213044 tn?1236527460
MMI is Methimazole.

These results are very confusing.

You have TBII antibodies, but your TSI is below upper limit. Was you TSI higher when you were diagnosed?

The dose of Methimazole and the dose of Levoxyl are both VERY small doses, and pretty much cancel each other out.

Your Free T4 and Free T3 are both quite low and show that you are hypothyroid, even though your TSH indicates you are hyper.

There is no denying that your Free T4 and Free T3 are too low. You are Hypothyroid.

Your TSH may be low because of a pituitary problem or an adrenal problem. It should be high, given your lack of T4/T3 hormones.

It doesn't look like Grave's at all, other than the TBII result.

Could you give a little more background information?
How you were diagnosed with Grave's, how long you have been treated, how do you feel, what kind of doctor you are seeing?
Helpful - 0
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