I am 49 year old female. On my recent bloodwork, my TSH reading was 0.50 mU/L. My previous TSH reading in April, 2008 was 1.65 mU/L and I was feeling good. I am currently on 0.1mg of Synthroid. My doctor did not recommend a change in dosage even though I do have symptoms of anxiety, depressed mood, tired eyes and general lack of energy. I would love some feedback on whether medication should be changed as the TSH levels fluctuate or whether this is normal during perimenopause and the fluctuation has to be drastic to warrant a change in dosage. I find the whole thing very frustrating since I don't like to blame all my problems on my thyroid - on the other hand, it controls so much it's hard not to!