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tyroid problem

hi
im female,50years old.I sweat so much and feeling sleepy aswell.I had a blood test recently and everything was normal except my cholesterol which is high a little and the TSH which is SO HIGH! it's about 40!
i met some doctors but it seems they don't know what's wrong with me.they all tell me "your test shows hypertyroidism but you sweat and sleep so much that is hypotyroidism symptoms!"
i really need help.
*NOTE:i don't take any pills recently.tnx
Best Answer
649848 tn?1534633700
COMMUNITY LEADER
Sounds like you need some different doctors.  

TSH is counter intuitive.  High TSH (yours is high, but we've seen much higher), typically, indicates hypothyroidism, not hyperthyroidism, as you say your doctors told you.   Secondly, the symptoms you mentioned - sweating and sleeping - could go either way.  Profuse sweating is, typically, a hyper symptom, while being sleepy is a symptom of both, hyper and hypo.

Is TSH the only test that was done?  If so, you should go back and tell them you want Free T3 and Free T4 done.  Those are actual thyroid hormones and will tell you exactly what's going on with your thyroid - whether it's over producing or under producing.  

Also tell them you want Thyroid Peroxidase Antibodies (TPOab), Thyroglobulin (TgAb) and Thyroid Stimulating Immunoglobulin (TSI) test done.  Those are all thyroid antibody tests.  The TPOab and TgAb will tell you whether or not you have Hashimoto's Thyroiditis and the TSI will tell you whether or not you have Graves Disease.  

Hashimoto's is, typically, associated with hypothyroidism, but can be characterized by periods of hyperthyroidism in early stages.  Graves Disease is always associated with hyperthyroidism
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649848 tn?1534633700
COMMUNITY LEADER
It's not always quite that simple and some people do have issues along the way, but we always hope it turns out that way.  

You shouldn't need the TSI test, since you aren't hyper and there's no reason to believe that you have Graves Disease.

Good luck.
Helpful - 0
Avatar universal
wow.thank you!
so all i need to do is to take some thyroid replacements and TPOab,TgAb and ultra sound,yes?do i need TSI test too?
anyway thanks a lot!
Helpful - 0
649848 tn?1534633700
COMMUNITY LEADER
Okay, correct me if I'm wrong, but here's what I'm getting, assuming that you're an adult:

T4    =  2.72   (range: 4.5-12.5)
T3    =  89      (range: 65-190)
TSH = 45.12   (range: 0.3-4.0)

As noted above, your TSH indicated hypothyroidism.  Since your T4 is below range (it's less than 4.5, which is the lower end of its range), this also indicates hypothyroidism.  Unfortunately, your doctor ordered Total T4, which is considered obsolete and of little value, since the majority of total T4 is bound by protein and isn't available for use.  This is why we test for the Free (unbound) portion of the T4 to see what's available for use.  Free T4 isn't used directly; it must be converted to T3. At any rate, since Total T4 is below range, it's safe to assume that Free T4 would be, as well.

Again, your doctor ordered Total T3, which is considered obsolete.  Like Total T4, most of it is bound by protein and is unavailable for use; therefore, we test the unbound (Free) portion to determine what is available.  Free T3 is the hormone that's used directly by the cells and largely controls metabolism, body temperature, heart rate and other body functions.

Has your doctor prescribed you any thyroid replacement medication yet?  If not, he needs to do so as soon as possible.

It's usually best to start out on a lower dosage (25-50 mcg) and work up slowly, as your body adjusts to having the medication.  you should retest every 5-6 weeks and make sure, from here on out that you get tested for FREE T3 and FREE T4... if not specified, you get only the tests for totals, like you got before.  Also ask for the TPOab and TgAb tests that I listed above... now that I see your actual results, there's no question about whether you're hypo or hyper -- there's nothing hyper about those test results and your symptoms are hypo, as well - even the sweating.

You may  have other symptoms of being hypo, also.  They could include fatigue (you mentioned being sleepy), weight gain, constipation, high cholesterol, muscle/joint aches/pains, hair loss, puffy face, swelling/edema, etc.

You might also ask for a thyroid ultra sound to determine whether or not you have nodules on your thyroid.  Many of us with Hashimoto's do and they are nothing to worry about, but should be checked out just to be sure.
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Avatar universal
here is my results:

Test--->Result--->Unit--->Method--->Reference interval
T4)      2.72*---ug/dl---CLIA---adults:4.5-12.5     Up to 2Y:3.52-17.4    2-4Y:3.7-15.7    4-12Y:3.91-14.4

T3)      89---ng/dl---CLIA---Adults:65-190    Up to 2 Y:33-256    2-4Y:42-248    4-12Y:41-231

T.S.H)     45.12*        microIU/ml       CLIA         adults:0.3-4      Up to 2Y:0.36-8.6       2-4Y:0.33-6.7        4-12Y:0.34-6.1

*=confirmed by repeated analysis
Helpful - 0
649848 tn?1534633700
COMMUNITY LEADER
If you had Free T3 and Free T4 tests done, please post the results and reference ranges, as those are much more important than TSH, since they are the actual thyroid hormones and will tell us exactly what's going on.  I can't imagine your doctors telling you that your TSH indicates hyper and your symptoms are hypo...

Your TSH indicates that you have hypothyroidism and will need to take replacement  thyroid hormones, because your thyroid doesn't produce enough.  You can't live, indefinitely without them. Typically, when people get worse on thyroid medications, it's when their doctors don't know what they're doing and only go by TSH, or think that being "in range" is good enough.  

Thyroid cancer is very rare and you have no reason to believe you might have it.
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Avatar universal
thank you!
actually i haven't TSH or T3,T4 tests separately if u mean that.the doctor told me you need a blood test and i found those in the blood test,i didn't mention T3 and T4 because their range was normal.
and...is my illness serious?I mean,I heard about some people who had hashimoto's or other tyroid disorders and after they took pills or other treatments their situation got worse!
Is there any possibility of cancer or some serious diseases like that?
Helpful - 0
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