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What else can high antihistone antibodies indicate?

I really NEED SOMEONE with medical expertise to PLEASE help me with my puzzle... everyday there are new pieces, but they only create more questions, and still no answers! I am fairly intelligent and able to research, with a decent amount of understanding, but I'm just not finding any answers! My recent bloodwork, consistent with previous bloodwork, shows a positive ANA with 1:320 titer, and a nucleolar pattern. But the puzzling part is the antihistone antibodies 7.3, normally indicative of drug induced lupus, but I've never taken any of the drugs associated with this... so I guess my question is WHAT ELSE could this point to?? All that keeps coming up is scleroderma, but I dont feel my symptoms fit this... I do feel they fit with sle, fibromyalgia, and even ms, but what about the antihistones? One other possible clue is my BUN/Creatinine ratio is slightly out of range (22.2)

I do have Hashimotos/hypothyroidism (controlled) but a laundry list of symptoms that go way beyond this... the doctors say fibromyalgia and chronic pain syndrome, which fits some of my symptoms, but doesnt explain the lab results and MANY other symptoms ...frankly it feels like the easy and common diagnosis without looking at the whole picture!

I could go on and on, but I wont (for now!) I can provide more puzzle pieces if needed, but for now my main question is regarding the antihistones...

I've read MANY of the very helpful threads and articles provided on this site, especially those by @thelightseeker (i really hope he sees this) but NOTHING on antihistones! So I signed up and here I am... ANY clues and advice would be appreciated!

Mahalo in advance :)
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363281 tn?1714899967
Hello~I have tried to do research on this, and I keep getting the same answers, that it is indicative of drug induced LUPUS and in  systemic lupus erythematosus (SLE). I suggest you have a heart to heart talk with your doctor and pin him down for answers.

Sorry I can not be of more help. I hope you find the answers you are looking for.
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I agree! Thank you so much, and you, as well :)
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