connection between small fibre Neuropathy and skin tags

[snowbird455]

is there a connection between small fibre neuropathy and Skin tags as the Skin tags and Neuropathy both developed about the same time. I have had all the neurologic examination neccesary to diagnose SFN and I noticed masses of skin tags forming around my neck under my breasts and hundreds of them forming down my spine. Understanding that SFN shows denervation in the epidermis, surely there must be a connection.


This discussion is related to Small Fiber Sensory Neuropathy.

[maatson]

Agree with redstar. But then going to specific connection, Amyloidisis is a condition with deposition of the amyloid material in the nerves leading to small fibre neuropathy. This is accompanied in somecases with skin tags.
The rarity and lack of knowledge of this association is responsible for not conducting special stains for amyloid.
You are an excellent observer for sure! Do consult your doc.

PRIMARY SYSTEMATISED AMYLOIDOSIS WITH STRIKING SKIN CHANGES*FF HELLIER - British Journal of Dermatology, 1959 - Wiley Online Library
... Numerous skin tags in the axillae may or may not have been part of the picture. ... As Symmers
(105(5) and other authors have shown, primary amyloidosis can manifest itself in many ways,
eg, heart failure, peri})heral neuropathy,

[Red_Star]

Medical conditions such as obesity, diabetes, insulin resistance and atherosclerosis are associated with more frequent skin tags.  Research findings in the May 2009 "Cleveland Clinic Journal of Medicine" article suggest that individuals with prediabetes or diabetes are at high risk for developing small fibre neuropathy.